Purpose Neurodegenerative diseases are associated with neuroinflammation along with
activation of microglia and oxidative stress, but currently lack effective treatments …

Scope In this study, the effects of punicalagin on neuroinflammation in LPS‐activated
microglia were investigated. Methods and results The ability of punicalagin to reduce the …

Introduction: Microglia-mediated inflammatory responses play a crucial role in aging-related
neurodegenerative diseases. The TXNIP/NLRP3 pathway is a key pathway leading to …

Microglial activation plays an important role in the development and progression of various
neurological disorders such as cerebral ischemia, multiple sclerosis, and Alzheimer's …

Isorhamnetin, which is a flavonoid predominantly found in fruits and leaves of various plants,
including Hippophae rhamnoides L. and Oenanthe javanica (Blume) DC, is known to …

The objective of the current study was to evaluate the anti-inflammatory effects of shizukaol
B, a lindenane-type dimeric sesquiterpene isolated from the whole plant of Chloranthus …

Background Inflammation has been found to be associated with many neurodegenerative
diseases, including Parkinson's and dementia. Attenuation of microglia-induced …

Background The NOD-like receptor family pyrin domain-containing 3 (NLRP3)
inflammasome is an important mediator of neuroinflammatory responses that regulates …

Scope In this study, it has been investigated whether the neuroprotective efficacy of
epigallocatechin‐3‐gallate (EGCG) is mediated by inhibition of canonical and noncanonical …

Microglia-associated neuroinflammation is recognized as a critical factor in the
pathogenesis of neurodegenerative diseases; however, there is no effective treatment for …