Punicalagin attenuates LPS-induced inflammation and ROS production in microglia by inhibiting the MAPK/NF-κB signaling pathway and NLRP3 inflammasome …
J Lo, CC Liu, YS Li, PY Lee, PL Liu, PC Wu… - Journal of …, 2022 - Taylor & Francis
Purpose Neurodegenerative diseases are associated with neuroinflammation along with
activation of microglia and oxidative stress, but currently lack effective treatments …
activation of microglia and oxidative stress, but currently lack effective treatments …
Punicalagin inhibits neuroinflammation in LPS‐activated rat primary microglia
OA Olajide, A Kumar, R Velagapudi… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope In this study, the effects of punicalagin on neuroinflammation in LPS‐activated
microglia were investigated. Methods and results The ability of punicalagin to reduce the …
microglia were investigated. Methods and results The ability of punicalagin to reduce the …
Panax notoginseng saponins attenuate neuroinflammation through TXNIP-mediated NLRP3 inflammasome activation in aging rats
Z Zhou, M He, Q Zhao, D Wang… - Current …, 2021 - ingentaconnect.com
Introduction: Microglia-mediated inflammatory responses play a crucial role in aging-related
neurodegenerative diseases. The TXNIP/NLRP3 pathway is a key pathway leading to …
neurodegenerative diseases. The TXNIP/NLRP3 pathway is a key pathway leading to …
[HTML][HTML] Kalopanaxsaponin A exerts anti-inflammatory effects in lipopolysaccharide-stimulated microglia via inhibition of JNK and NF-κB/AP-1 pathways
YH Jeong, JW Hyun, TK Van Le, DH Kim… - Biomolecules & …, 2013 - ncbi.nlm.nih.gov
Microglial activation plays an important role in the development and progression of various
neurological disorders such as cerebral ischemia, multiple sclerosis, and Alzheimer's …
neurological disorders such as cerebral ischemia, multiple sclerosis, and Alzheimer's …
Isorhamnetin alleviates lipopolysaccharide-induced inflammatory responses in BV2 microglia by inactivating NF-κB, blocking the TLR4 pathway and reducing ROS …
SY Kim, CY Jin, CH Kim, YH Yoo… - International …, 2019 - spandidos-publications.com
Isorhamnetin, which is a flavonoid predominantly found in fruits and leaves of various plants,
including Hippophae rhamnoides L. and Oenanthe javanica (Blume) DC, is known to …
including Hippophae rhamnoides L. and Oenanthe javanica (Blume) DC, is known to …
Shizukaol B, an active sesquiterpene from Chloranthus henryi, attenuates LPS-induced inflammatory responses in BV2 microglial cells
The objective of the current study was to evaluate the anti-inflammatory effects of shizukaol
B, a lindenane-type dimeric sesquiterpene isolated from the whole plant of Chloranthus …
B, a lindenane-type dimeric sesquiterpene isolated from the whole plant of Chloranthus …
Corylin inhibits LPS-induced inflammatory response and attenuates the activation of NLRP3 inflammasome in microglia
Background Inflammation has been found to be associated with many neurodegenerative
diseases, including Parkinson's and dementia. Attenuation of microglia-induced …
diseases, including Parkinson's and dementia. Attenuation of microglia-induced …
[HTML][HTML] Salidroside inhibits NLRP3 inflammasome activation and apoptosis in microglia induced by cerebral ischemia/reperfusion injury by inhibiting the TLR4/NF-κB …
J Liu, W Ma, CH Zang, GD Wang… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background The NOD-like receptor family pyrin domain-containing 3 (NLRP3)
inflammasome is an important mediator of neuroinflammatory responses that regulates …
inflammasome is an important mediator of neuroinflammatory responses that regulates …
Epigallocatechin‐3‐gallate attenuates microglial inflammation and neurotoxicity by suppressing the activation of canonical and noncanonical inflammasome via TLR4 …
X Zhong, M Liu, W Yao, K Du, M He… - Molecular nutrition & …, 2019 - Wiley Online Library
Scope In this study, it has been investigated whether the neuroprotective efficacy of
epigallocatechin‐3‐gallate (EGCG) is mediated by inhibition of canonical and noncanonical …
epigallocatechin‐3‐gallate (EGCG) is mediated by inhibition of canonical and noncanonical …
Nordalbergin exerts anti-neuroinflammatory effects by attenuating MAPK signaling pathway, NLRP3 inflammasome activation and ROS production in LPS-stimulated …
J Lo, HE Wu, CC Liu, KC Chang, PY Lee… - International Journal of …, 2023 - mdpi.com
Microglia-associated neuroinflammation is recognized as a critical factor in the
pathogenesis of neurodegenerative diseases; however, there is no effective treatment for …
pathogenesis of neurodegenerative diseases; however, there is no effective treatment for …
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