Corticosteroids in idiopathic pulmonary fibrosis

JP Lynch III, E White, K Flaherty - Current opinion in pulmonary …, 2001 - journals.lww.com
Corticosteroids were the mainstay of therapy for idiopathic pulmonary fibrosis (IPF) for more
than four decades, but their efficacy is unproven and toxicities are substantial. The course of …

[HTML][HTML] Corticosteroids and the treatment of idiopathic pulmonary fibrosis: past, present, and future

DW Mapel, JM Samet, DB Coultas - Chest, 1996 - Elsevier
Why are corticosteroids used in patients with IPF? There is evidence that corticosteroid
therapy is associated with clinical improvement in only a small percentage of IPF patients …

Combined corticosteroid and cyclophosphamide therapy does not alter survival in idiopathic pulmonary fibrosis

HR Collard, JH Ryu, WW Douglas, MI Schwarz… - Chest, 2004 - Elsevier
Study objectives Treatment of patients with idiopathic pulmonary fibrosis (IPF)
conventionally includes corticosteroids and cytotoxic agents. No study to date has …

Therapeutic management of idiopathic pulmonary fibrosis: an evidence-based approach

SD Nathan - Clinics in chest medicine, 2006 - chestmed.theclinics.com
Idiopathic pulmonary fibrosis (IPF), also known as cryptogenic fibrosing alveolitis, is a
distinct form of interstitial lung disease of unknown etiology that is limited to the lung; it is …

Idiopathic pulmonary fibrosis: a need for treatment with drugs other than corticosteroids—a role for antifibrotic agents?

G Raghu - Mayo Clinic Proceedings, 1997 - mayoclinicproceedings.org
Idiopathic pulmonary fibrosis (IPF) is a highly lethal disorder associated with an extremely
poor prognosis and poor survival in most patients. Higher mortality rates attributable to …

Idiopathic pulmonary fibrosis: current and future treatment options

HR Davies, L Richeldi - American Journal of Respiratory Medicine, 2002 - Springer
Idiopathic pulmonary fibrosis (IPF) is a chronic condition of unknown etiology with an
unfavorable outcome from progressively deteriorating respiratory function, leading ultimately …

[HTML][HTML] Corticosteroid and immunomodulatory agents in idiopathic pulmonary fibrosis

F Luppi, S Cerri, B Beghè, LM Fabbri, L Richeldi - Respiratory medicine, 2004 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary disease leading to death
within a few years of diagnosis despite medical therapy. On the basis of methodologies of …

Factors associated with the use of corticosteroids in the initial management of idiopathic pulmonary fibrosis

JC Munson, M Kreider, Z Chen… - … and drug safety, 2010 - Wiley Online Library
Purpose Idiopathic pulmonary fibrosis (IPF) has not been shown to respond to corticosteroid
therapy; however, many patients receive these drugs at the time of diagnosis. The factors …

Steroids in idiopathic pulmonary fibrosis: a prospective assessment of adverse reactions, response to therapy, and survival

KR Flaherty, GB Toews, JP Lynch III… - The American journal of …, 2001 - Elsevier
PURPOSE: We evaluated the risk and potential benefit of high-dose corticosteroid therapy in
patients with idiopathic pulmonary fibrosis. SUBJECTS AND METHODS: We prospectively …

[HTML][HTML] Survival in idiopathic pulmonary fibrosis—cytotoxic agents compared to corticosteroids

CAC Pereira, T Malheiros, EM Coletta, RG Ferreira… - Respiratory …, 2006 - Elsevier
STUDY OBJECTIVE: To compare the survival of patients with IPF treated retrospectively with
corticosteroids alone, to survival of patients treated with immunosuppressive and …