The NOD like receptors (NLRs), a class of intracellular receptors that respond to pathogen
attack or cellular stress, have gained increasing attention. NLRC5, the largest member of the …

NLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization
domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating …

Innate immunity activates the corresponding immune response relying on multiple pattern
recognition receptors (PRRs) that includes pattern recognition receptors (PRRs), like NOD …

NOD-like receptors (NLRs) are a family of intracellular proteins that play critical roles in
innate immunity against microbial infection. NLRC5, the largest member of the NLR family …

Stringent control of the NF-κB and type I interferon signaling pathways is critical to effective
host immune responses, yet the molecular mechanisms that negatively regulate these …

NLRC5 is a member of the NLR family that acts as a transcriptional activator of MHC class I
genes. In line with the function of several related NLR proteins in innate immune responses …

The innate immune system is the first line of defense for the host against any microbial
attack. It can quickly identify microorganisms and produce an immune response, removing …

Intracellular NOD-like receptor (NLR) proteins are believed to play important roles in innate
immune detection or immune regulation, but only a few NLR proteins are functionally …

Members of the nucleotide-binding and oligomerization domain (NOD)-like receptor (NLR)
family are quickly emerging as critical regulators of innate and adaptive immune responses …

Nod-like receptors (NLRs) are intracellular sentinel proteins that are implicated in the
detection of microbes and danger signals, thereby controlling several key innate immune …