Although the etiology of multiple sclerosis (MS) remains enigmatic, the role of T cells is
unquestionably central in this pathology. Immune cells respond to pathogens and danger …

Nucleotide-binding leucine-rich repeat-containing proteins, or NOD-like receptors (NLRs),
are intracellular innate immune sensors that can regulate several signaling pathways …

Nucleotide-binding domain and leucine-rich repeat (NLR) proteins play important roles in
innate immune responses as pattern-recognition receptors. Although most NLR proteins act …

NOD-like receptors (NLRs) are a class of cytoplasmic pattern-recognition receptors.
Although most NLRs play some role in immunity, their functions range from regulating …

The presentation of antigenic peptides by major histocompatibility complex (MHC) class I
and class II molecules is crucial for activation of the adaptive immune system. The …

Inflammasomes are cytosolic multiprotein complexes that sense microbial infections or host
cell damage, triggering cytokine production and a proinflammatory form of cell death, called …

NOD‐like receptor (NLR) family CARD domain containing 3 (NLRC 3), an intracellular
member of NLR family, is a negative regulator of inflammatory signaling pathways in innate …

Nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) are a group of
cytoplasmic sensors that survey danger signals released by invading pathogen or damaged …

Both NLRC3 and NOD1 belong to regulatory NLR subfamily based on their best-
characterized function. In mammals, NLRC3 was reported to function by attenuating …

Intracellular NOD-like receptors (NLRs) are emerging as critical regulators of innate and
adaptive immune responses. Although the NLR family member NLRC5 is functionally …