Mechanical ventilation is a life-support system used to ensure blood gas exchange and to
assist the respiratory muscles in ventilating the lung during the acute phase of lung disease …

It was recently shown that acute respiratory distress syndrome (ARDS) mortality has not
been reduced in over 15 years and remains~ 40%, even with protective low tidal volume …

Patients with severe lung injury usually have a high respiratory drive, resulting in intense
inspiratory effort that may even worsen lung damage by several mechanisms gathered …

Once upon a time the existence of ventilator-induced lung injury (VILI) was debated. After all,
most patients with lung dysfunction requiring mechanical ventilation had other potential …

How ventilation strategy, specific mechanisms of mechanotransduction, and their individual
threshold values impact on VALI remains to be elucidated. In addition, clinical studies are …

The pathophysiological mechanisms by which mechanical ventilation can contribute to lung
injury, termed “ventilator-induced lung injury”(VILI), is increasingly well understood.“ …

Mechanical ventilation can produce lung physiological and morphological alterations
termed ventilator-induced lung injury (VILI). Early experimental studies demonstrated that …

Although mechanical ventilation (MV) is a life-saving intervention for patients with acute
respiratory distress syndrome (ARDS), it can aggravate or cause lung injury, known as …

During assisted mechanical ventilation, spontaneous inspiratory effort can cause both lung
(patient self-inflicted lung injury [P-SILI]) and diaphragm injury. While clinicians are primarily …

Introduction: Mechanical ventilation is required to support respiratory function in the acute
respiratory distress syndrome (ARDS), but it may promote lung damage, a phenomenon …