Traditional Chinese medicine (TCM) formulas have attracted increasing attention worldwide
in the past few years for treating complex disease including rheumatoid arthritis. However …

Ginsenoside compound K (GCK) has been previously reported to be a potent antiarthritic
and bone‑protective agent. Therefore, the present study aimed to explore the potential …

Background Some studies have indicated that glucose metabolism plays an important role
in the pathogenesis of rheumatoid arthritis (RA). This study aimed to find the novel genes …

The anti-inflammatory actions of glucosamine (GlcN) on arthritic disorders involve the
suppression of inflammatory mediator production from synovial cells. GlcN has also been …

Ginsenoside metabolite compound K (CK) is the degradation product of ginsenosides in the
intestine by bacteria and has many pharmacological activities including anti-inflammatory …

Rheumatoid arthritis (RA) is potentially devastating condition which lacks good treatment
options. Pro‐inflammatory cytokines interleukin‐1beta (IL‐1β), tumor necrosis factor‐alpha …

Osteoarthritis (OA) is an age-related metabolic disease. Low-grade inflammation and
oxidative stress are the last common pathway of OA. α-ketoglutarate (α-KG) is an essential …

Objective Rheumatoid arthritis (RA) is mainly characterized by synovial hyperplasia,
angiogenesis, inflammatory cells infiltration. Chymotrypsin is a proteolytic enzyme with anti …

Strategies for treating osteoarthritis (OA) have become a research focus because an
effective treatment for OA is unavailable. The objective of this study was to explore the …

Osteoarthritis (OA) is a serious and frequently occurring disease in the elderly, characterized
by cartilage degeneration and proliferation of bone structure. Glycyrrhizin, a compound …