In this study, we attempted to identify and assess effects of isoegomaketone (IK) isolated
from Perilla frutescens var. crispa on the development of rheumatoid arthritis (RA). RA was …

Objective This study examined the anti-inflammatory and chondroprotective effects of
compound K (CK), a ginsenoside metabolite, on chondrocytes from osteoarthritis (OA) …

Total glucosides of paeony (TGP) are active compounds extracted from the roots of Paeonia
lactiflora Pall. In this study, we investigated the mechanisms of total glucosides of paeony …

Blockade of Hedgehog signaling can prevent osteoarthritis (OA) syndromes. However, the
amelioration of related inflammation condition is limited. The purpose of this study was to …

Background: Rheumatoid arthritis (RA) is a chronic articular synovial inflammatory disease.
The precise etiology underlying the pathogenesis of RA remains unknown. We aimed to …

Rheumatoid arthritis (RA), an inflammatory autoimmune disease that causes cartilage
degradation and tissue destruction, can affect synovial joints such as the knee joint. The link …

Stimulating fibroblast-like synoviocyte (FLS) apoptosis in rheumatoid arthritis (RA) is a
promising strategy for clinical treatment. Previous studies have confirmed that geniposide …

Osteoarthritis (OA) is a prevalent degenerative disease that impairs limb function, and its
pathogenesis is closely related to inflammation. Sakuranetin (SK) is a cherry flavonoid …

Aim Rheumatoid arthritis is a chronic inflammatory autoimmune disorder with multi‐factorial
factors influencing disease alleviation in synovial joints. The aim of this study was to …

Objective Osteoarthritis (OA), the most common chronic degenerative joint disease, is
characterized by joint structure changes and inflammation, both mediated by the IκB kinase …