Stimulating fibroblast-like synoviocyte (FLS) apoptosis in rheumatoid arthritis (RA) is a
promising strategy for clinical treatment. Previous studies have confirmed that geniposide …

Both hyaluronic acid (HA) and cyclooxygenase-2 (COX-2) inhibitors are used in clinical
practice in the treatment of osteoarthritis. There have been no reports regarding cross-talk …

Osteoarthritis (OA) is driven by chronic low-grade inflammation and subsequent cartilage
degradation. OA is the most prevalent degenerative joint disease worldwide, and its …

Blockade of Hedgehog signaling can prevent osteoarthritis (OA) syndromes. However, the
amelioration of related inflammation condition is limited. The purpose of this study was to …

Background: Rheumatoid arthritis (RA) is a chronic articular synovial inflammatory disease.
The precise etiology underlying the pathogenesis of RA remains unknown. We aimed to …

Osteoarthritis (OA) is a prevalent degenerative disease that impairs limb function, and its
pathogenesis is closely related to inflammation. Sakuranetin (SK) is a cherry flavonoid …

Objective Osteoarthritis (OA), the most common chronic degenerative joint disease, is
characterized by joint structure changes and inflammation, both mediated by the IκB kinase …

Gypenoside (GP), the main active ingredient of Gynostemma pentaphyllum, possesses a
variety of pharmacological capacities including anti‐inflammation, anti‐oxidation, and anti …

Isorhamnetin (ISH) is a flavonoid primarily obtained from the fruit of Hippophae rhamnoides
L., which possesses anti‑inflammatory properties. However, the effect of ISH on the …