Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity
LML Bezerra, SG Filler - Blood, 2004 - ashpublications.org
Invasive aspergillosis causes significant mortality among patients with hematologic
malignancies. This infection is characterized by vascular invasion and thrombosis. To study …
malignancies. This infection is characterized by vascular invasion and thrombosis. To study …
Interactions of Aspergillus fumigatus with vascular endothelial cells
Y Kamai, LY Chiang, LM Lopes Bezerra… - Medical …, 2006 - academic.oup.com
Invasive aspergillosis is characterized by two different types of angioinvasion. During
pulmonary aspergillosis, hyphae are initially outside of the pulmonary vasculature and they …
pulmonary aspergillosis, hyphae are initially outside of the pulmonary vasculature and they …
Aspergillus fumigatus Stimulates Leukocyte Adhesion Molecules and Cytokine Production by Endothelial Cells In Vitro and during Invasive Pulmonary Disease
LY Chiang, DC Sheppard, FN Gravelat… - Infection and …, 2008 - Am Soc Microbiol
Invasive aspergillosis is characterized by hyphal invasion of the blood vessels, which
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus …
contributes to the pathogenesis of this disease. During this angioinvasion, Aspergillus …
Polarized response of endothelial cells to invasion by Aspergillus fumigatus
Y Kamai, AS Lossinsky, H Liu… - Cellular …, 2009 - Wiley Online Library
Hyphal invasion of blood vessels is a prominent feature of invasive aspergillosis. During
invasive pulmonary aspergillosis, Aspergillus fumigatus hyphae invade the abluminal …
invasive pulmonary aspergillosis, Aspergillus fumigatus hyphae invade the abluminal …
Aspergillus fumigatus inhibits angiogenesis through the production of gliotoxin and other secondary metabolites
In susceptible hosts, angioinvasion by Aspergillus fumigatus triggers thrombosis, hypoxia,
and proinflammatory cytokine release, all of which are stimuli for angiogenesis. We sought …
and proinflammatory cytokine release, all of which are stimuli for angiogenesis. We sought …
Identification of genes of Aspergillus fumigatus up-regulated during growth on endothelial cells
JC Rhodes, BG Oliver, DS Askew… - Medical …, 2001 - academic.oup.com
Aspergillus fumigatus is an important opportunistic fungal pathogen that can cause acute
invasive disease in neutropenic hosts. Invasive aspergillosis is being diagnosed with …
invasive disease in neutropenic hosts. Invasive aspergillosis is being diagnosed with …
Fungal invasion of normally non-phagocytic host cells
SG Filler, DC Sheppard - PLoS pathogens, 2006 - journals.plos.org
Many fungi that cause invasive disease invade host epithelial cells during mucosal and
respiratory infection, and subsequently invade endothelial cells during hematogenous …
respiratory infection, and subsequently invade endothelial cells during hematogenous …
Aspergillus fumigatus Activates Thrombocytes by Secretion of Soluble Compounds
C Speth, M Hagleitner, HW Ott… - The Journal of …, 2013 - academic.oup.com
During invasive aspergillosis, platelets might be involved in immune defense, but they also
might contribute to the pathology of the disease. We tested the hypothesis that Aspergillus …
might contribute to the pathology of the disease. We tested the hypothesis that Aspergillus …
Enemy of the (immunosuppressed) state: an update on the pathogenesis of Aspergillus fumigatus infection
Aspergillus fumigatus is an opportunistic filamentous fungus that is currently the most
frequent cause of invasive fungal disease in immunosuppressed individuals. Recent …
frequent cause of invasive fungal disease in immunosuppressed individuals. Recent …
Intracellular and extracellular growth of Aspergillus fumigatus
JA Wasylnka, AHT Hissen, ANC Wan… - Medical mycology, 2005 - Taylor & Francis
Aspergillus fumigatus is a filamentous fungus that can cause a life-threatening systemic
mycosis in immunocompromised patients. We have studied the growth of A. fumigatus inside …
mycosis in immunocompromised patients. We have studied the growth of A. fumigatus inside …