[HTML][HTML] Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease
Aims Patients with chronic kidney disease (CKD) have an increased risk of cardiovascular
events and exhibit myocardial changes including left ventricular (LV) hypertrophy and …
events and exhibit myocardial changes including left ventricular (LV) hypertrophy and …
[HTML][HTML] A systematic review and meta-analysis of murine models of uremic cardiomyopathy
Chronic kidney disease (CKD) triggers the risk of developing uremic cardiomyopathy as
characterized by cardiac hypertrophy, fibrosis and functional impairment. Traditionally …
characterized by cardiac hypertrophy, fibrosis and functional impairment. Traditionally …
[HTML][HTML] Shared and Distinct Renal Transcriptome Signatures in 3 Standard Mouse Models of Chronic Kidney Disease
AB Marstrand-Jørgensen, FE Sembach, ST Bak… - Nephron, 2024 - karger.com
Introduction: Several mouse models with diverse disease etiologies are used in preclinical
research for chronic kidney disease (CKD). Here, we performed a head-to-head comparison …
research for chronic kidney disease (CKD). Here, we performed a head-to-head comparison …
Cardiac remodeling in chronic kidney disease
Cardiac remodeling occurs frequently in chronic kidney disease patients and affects quality
of life and survival. Current treatment options are highly inadequate. As kidney function …
of life and survival. Current treatment options are highly inadequate. As kidney function …
Cardiomyopathy in chronic kidney disease: clinical features, biomarkers and the contribution of murine models in understanding pathophysiology
CVC Junho, J Frisch, J Soppert… - Clinical Kidney …, 2023 - academic.oup.com
The cardiorenal syndrome (CRS) is described as a multi‐organ disease encompassing
bidirectionally heart and kidney. In CRS type 4, chronic kidney disease (CKD) leads to …
bidirectionally heart and kidney. In CRS type 4, chronic kidney disease (CKD) leads to …
Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction
Ischemic heart disease is the leading cause of death worldwide and is frequently comorbid
with chronic kidney disease. Physiological communication is known to occur between the …
with chronic kidney disease. Physiological communication is known to occur between the …
Mapping cardiac remodeling in chronic kidney disease
Patients with advanced chronic kidney disease (CKD) mostly die from sudden cardiac death
and recurrent heart failure. The mechanisms of cardiac remodeling are largely unclear. To …
and recurrent heart failure. The mechanisms of cardiac remodeling are largely unclear. To …
In chronic kidney disease altered cardiac metabolism precedes cardiac hypertrophy
Conduit arterial disease in chronic kidney disease (CKD) is an important cause of cardiac
complications. Cardiac function in CKD has not been studied in the absence of arterial …
complications. Cardiac function in CKD has not been studied in the absence of arterial …
Redox signalling and cardioprotection: translatability and mechanism
P Pagliaro, C Penna - British Journal of Pharmacology, 2015 - Wiley Online Library
The morbidity and mortality from coronary artery disease (CAD) remain significant
worldwide. The treatment for acute myocardial infarction has improved over the past …
worldwide. The treatment for acute myocardial infarction has improved over the past …
[HTML][HTML] Experimental coronary artery stenosis accelerates kidney damage in renovascular hypertensive swine
The impact of coronary artery stenosis (CAS) on renal injury is unknown. Here we tested
whether the existence of CAS, regardless of concurrent atherosclerosis, would induce …
whether the existence of CAS, regardless of concurrent atherosclerosis, would induce …