SGLT2 inhibitors DELIVER benefits in heart failure independently of ejection fraction and diabetes: end of the line or need for new studies?
M Volpe, D Pedicino - 2022 - academic.oup.com
• DELIVER (Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection
Fraction) 1 is an industry-funded Phase 3, double-blind, event-driven, randomized …
Fraction) 1 is an industry-funded Phase 3, double-blind, event-driven, randomized …
[引用][C] SGLT-2 inhibitors in heart failure: An updated systematic review and meta-analysis of 13 randomized clinical trials including 14618 patients with heart failure
Sodium-glucose cotransporter 2 inhibitors: the first universal treatment for heart failure?
K McDowell, KF Docherty - … Heart Journal-Quality of Care and …, 2022 - academic.oup.com
In 2015, publication of the results of the BI 10773 (empagliflozin) Cardiovascular Outcome
Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME) heralded the …
Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME) heralded the …
Effects of SGLT2 inhibitors on cardiovascular, renal, and major safety outcomes in heart failure: a meta-analysis of randomized controlled trials
X Li, Q Zhang, L Zhu, G Wang, P Ge, A Hu… - International Journal of …, 2021 - Elsevier
Aims Sodium-glucose co-transporter 2 inhibitor (SGLT2i), initially introduced for the
treatment of diabetes mellitus (DM), demonstrates cardiovascular and renal benefits in …
treatment of diabetes mellitus (DM), demonstrates cardiovascular and renal benefits in …
Diamonds in the Rough: The incredible-but-true story of sodium glucose cotransporter 2 inhibitors in treatment of heart failure
M Kosiborod - Circulation, 2021 - Am Heart Assoc
An old story describes a farmer who led a contented life until he found out about the
existence of precious stones. He became so fascinated with diamonds, that he traveled …
existence of precious stones. He became so fascinated with diamonds, that he traveled …
Clinical pharmacology of SGLT-2 inhibitors in heart failure
M Velliou, E Polyzogopoulou, I Ventoulis… - Expert Review of …, 2023 - Taylor & Francis
Introduction Sodium-glucose cotransporter 2 (SGLT2) inhibitors constitute a class of oral
antiglycemic agents that have emerged as a new therapeutic strategy for heart failure (HF) …
antiglycemic agents that have emerged as a new therapeutic strategy for heart failure (HF) …
Sodium-glucose cotransporter 2 inhibitors in heart failure
KS Shah, JC Fang - Annual Review of Pharmacology and …, 2022 - annualreviews.org
Sodium-glucose cotransporter 2 (SGLT2) inhibitors improve blood glucose control by
blocking renal glucose reabsorption with little subsequent risk of hypoglycemia …
blocking renal glucose reabsorption with little subsequent risk of hypoglycemia …
[引用][C] Comment on SGLT-2 inhibitors for treatment of heart failure in patients with and without type 2 diabetes: A practical approach for routine clinical practice
B Azeem, R Asim - International …, 2023 - internationaljournalofcardiology.com
Primarily, a comprehensive view of the cost considerations for prescribing SGLT-2i has been
excluded, as accessibility and affordability of these medications in deprived regions …
excluded, as accessibility and affordability of these medications in deprived regions …
DAPA-HF study: Are the benefits uniform across non-diabetic subgroups
A Pareek, R Rajput, HK Chopra… - Indian Heart …, 2020 - ncbi.nlm.nih.gov
Large clinical trials involving type 2 diabetes (T2D) patients have shown that sodium-
glucose transporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure …
glucose transporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure …
Efficacy and safety of SGLT2 inhibitors in patients with heart failure: A protocol for systematic review and meta-analysis
L Wang, X Guo - Medicine, 2022 - journals.lww.com
Background: Heart failure (HF) prognosis without therapy is poor, however introduction of a
range of drugs has improved it. We aimed to perform a protocol for systematic review and …
range of drugs has improved it. We aimed to perform a protocol for systematic review and …