[HTML][HTML] CD4+ T-cell responses mediate progressive neurodegeneration in experimental ischemic retinopathy
Retinal ischemic events, which result from occlusion of the ocular vasculature share similar
causes as those for central nervous system stroke and are among the most common cause …
causes as those for central nervous system stroke and are among the most common cause …
Immune cells in subretinal wound healing and fibrosis
M Szczepan, M Llorián-Salvador, M Chen… - Frontiers in Cellular …, 2022 - frontiersin.org
The subretinal space is devoid of any immune cells under normal conditions and is an
immune privileged site. When photoreceptors and/or retinal pigment epithelial cells suffer …
immune privileged site. When photoreceptors and/or retinal pigment epithelial cells suffer …
Minocycline modulates microglia polarization in ischemia-reperfusion model of retinal degeneration and induces neuroprotection
Retinal ischemia-reperfusion (IR) injury causes irreversible loss of neurons and ultimately
leads to permanent visual impairment and blindness. The cellular response under this …
leads to permanent visual impairment and blindness. The cellular response under this …
Optic nerve degeneration after retinal ischemia/reperfusion in a rodent model
M Renner, G Stute, M Alzureiqi, J Reinhard… - Frontiers in cellular …, 2017 - frontiersin.org
Retinal ischemia is a common pathomechanism in many ocular disorders such as age-
related macular degeneration (AMD), diabetic retinopathy, glaucoma or retinal vascular …
related macular degeneration (AMD), diabetic retinopathy, glaucoma or retinal vascular …
Colony-stimulating factor 1 receptor inhibition prevents disruption of the blood-retina barrier during chronic inflammation
D Kokona, A Ebneter, P Escher… - Journal of …, 2018 - Springer
Background Microglia-associated inflammation is closely related to the pathogenesis of
various retinal diseases such as uveitis and diabetic retinopathy, which are associated with …
various retinal diseases such as uveitis and diabetic retinopathy, which are associated with …
[HTML][HTML] Vitreous cytokine expression and a murine model suggest a key role of microglia in the inflammatory response to retinal detachment
L Kiang, BX Ross, J Yao, S Shanmugam… - … & visual science, 2018 - tvst.arvojournals.org
Purpose: Retinal detachment (RD) separates the retina from the underlying retinal pigment
epithelium, resulting in a gradual degeneration of photoreceptor (PR) cells. It is known that …
epithelium, resulting in a gradual degeneration of photoreceptor (PR) cells. It is known that …
Blood-retinal barrier breakdown following experimental retinal ischemia and reperfusion
CA Wilson, BA Berkowitz, H Funatsu, DC Metrikin… - Experimental eye …, 1995 - Elsevier
The purpose of this study was to examine the effects of acute ischemia and reperfusion on
blood-retinal barrier (BRB) function in the rabbit eye. Hydrostatic pressure (140 mmHg) was …
blood-retinal barrier (BRB) function in the rabbit eye. Hydrostatic pressure (140 mmHg) was …
Inhibiting multiple forms of cell death optimizes ganglion cells survival after retinal ischemia reperfusion injury
Q Qin, N Yu, Y Gu, W Ke, Q Zhang, X Liu, K Wang… - Cell death & …, 2022 - nature.com
Progressive retinal ganglion cells (RGCs) death that triggered by retinal ischemia
reperfusion (IR), leads to irreversible visual impairment and blindness, but our knowledge of …
reperfusion (IR), leads to irreversible visual impairment and blindness, but our knowledge of …
Interleukin-6 in retinal ischemia reperfusion injury in rats
RN Sanchez, CK Chan, S Garg… - … & visual science, 2003 - iovs.arvojournals.org
purpose. To study the role of interleukin (IL)-6 after retinal ischemia–reperfusion (I/R) injury
in rats. methods. Intraocular pressure of adult male Lewis albino rats was raised to create …
in rats. methods. Intraocular pressure of adult male Lewis albino rats was raised to create …
Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina
KA Church, D Rodriguez, D Vanegas… - Journal of …, 2022 - Springer
Microglia, the resident phagocytes of the retina, are believed to influence the development of
retinopathy, but their exact contributions to vascular integrity and neuronal loss are …
retinopathy, but their exact contributions to vascular integrity and neuronal loss are …