The bisindole moiety, as a versatile pharmacophore, is one of the widespread heterocycles
in naturally occurring and synthetic bioactive compounds. The bisindole alkaloids derived …

Currently, the number of new cancer cases and deaths worldwide is increasing year on
year. In addition to the requirement for cancer prevention, the top priority is still to seek the …

Original cytotoxic bisindole alkaloids with a 1, 2, 3, 4-tetrahydroquinoline bridge were
synthesized by reductive amination with various anilines. The most cytotoxic compounds …

The past several years have seen an increase in the discovery and isolation of natural
products of the indole alkaloid class. Bis-and tris-indole alkaloids are classes of natural …

This chapter covers the literature on bisindole alkaloids consisting of monoterpenoid
indoles, published up to June 2015. Bisindole alkaloids isolated from plants belonging to the …

In a relatively short period of time several bis-indole alkaloids, especially those from
Catharunfhus roseus G. Don, have became highly valuable agents in chemotherapy. The …

Indole, a heterocyclic organic compound, is one of the most promising heterocycles found in
natural and synthetic sources since its derivatives possess fascinating structural diversity …

Two new ring systems, isoindolo [1, 4] benzoxazinone and isoindolo [1, 5] benzoxazepine,
were conveniently synthesized through cyclization of suitably substituted isoindole …

Two alternative routes have been developed for the synthesis of trichotomine dimethyl ester
2. Both routes involve the synthesis of keto lactam 3 by reaction of the chiral imine 4 …

Recent progress in the chemistry of non-monoterpenoid indole alkaloids Page 1 Recent
progress in the chemistry of non-monoterpenoid indole alkaloids Masahiro Toyota and Masataka …