Synthesis and pharmacological evaluation of novel bisindole derivatives bearing oximes moiety: Identification of novel proapoptotic agents

HE Qu, RZ Huang, GY Yao, JL Li, MY Ye… - European Journal of …, 2015 - Elsevier
In an effort to develop potent anti-cancer chemopreventive agents, a novel series of
bisindole derivatives bearing oxime moiety were synthesized. Structures of all compounds …

Methods for the construction of [1, 2] isoindolo-condensed benzazepines, benzazocines, quinolines, and isoquinolines. 2. Isoindoloquinolines, isoindoloisoquinolines.

EV Boltukhina, FI Zubkov, AV Varlamov - Chemistry of Heterocyclic …, 2006 - Springer
Data for 1966–2004 on methods for the construction of tetracyclic systems in which an
isoindole ring is condensed with quinoline and isoquinoline fragments on the [1, 2] side are …

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

M Lounasmaa, A Tolvanen - Natural product reports, 2000 - pubs.rsc.org
2.1. 4 Indoloquinolines 2.2 Non-isoprenoid tryptamines 2.2. 1 Piperazinediones 2.2. 2
Physostigmine and related compounds 2.2. 3 Indoloiminoquinones 2.2. 4 b-Carbolines 2.2 …

Angustifonines A and B, Cytotoxic Bisindole Alkaloids from Bousigonia angustifolia

Y Fu, Y Di, H He, S Li, Y Zhang… - Journal of Natural …, 2014 - ACS Publications
Two new bisindole alkaloids, angustifonines A (1) and B (2), comprising the union of a
rearranged monoterpenoid quinoline and an aspidospermine alkaloid, as well as 27 known …

A convenient preparation of 4-iodoindoles from indoles: application to the chemical synthesis of hapalindole alkaloids

MA Brown, MA Kerr - Tetrahedron Letters, 2001 - Elsevier
4-Iodoindoles were synthesized via regioselective chloromercuration and subsequent
iodination of a series of Np-toluenesulfonyl indoles bearing a variety of substituents at the 3 …

Asymmetric synthesis of phenanthroindolizidine alkaloids with hydroxyl group at the C14 position and evaluation of their antitumor activities

T Ikeda, T Yaegashi, T Matsuzaki, S Hashimoto… - Bioorganic & medicinal …, 2011 - Elsevier
The asymmetric total synthesis of the strongly cytotoxic phenanthroindolizidine alkaloid 3
was achieved. Using the same route, various derivatives were also synthesized. Cytotoxicity …

Phenanthroindolizidines and phenanthroquinolizidines: promising alkaloids for anti-cancer therapy

SR Chemler - Current bioactive compounds, 2009 - ingentaconnect.com
The phenanthroindolizidine and phenanthroquinolizidine alkaloids, typified by tylophorine
and cryptopleurine, are a family of plant-derived small molecules with significant therapeutic …

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

S Hibino, T Choshi - Natural product reports, 2002 - pubs.rsc.org
Covering: January 2000 to December 2000. Previous review: 2001, 18, 66. This review
covers simple indole alkaloids, isoprenoid tryptamines, and bisindole alkaloids with a …

Simple indole alkaloids and those with a nonrearranged monoterpenoid unit

S Hibino, T Choshi - Natural product reports, 2001 - pubs.rsc.org
2.1. 4 Indoloquinolines 2.2 Non-isoprenoid tryptamines 2.2. 1 Piperazinediones 2.2. 2
Physostigmine and related compounds 2.2. 3 Indoloiminoquinones 2.2. 4 β-Carbolines 2.2 …

Synthesis of new heteroaryl and heteroannulated indoles from dehydrophenylalanines: Antitumor evaluation

MJRP Queiroz, AS Abreu, MSD Carvalho… - Bioorganic & medicinal …, 2008 - Elsevier
A 3-(dibenzothien-4-yl) indole and a phenylbenzothienoindole or a 3-(dibenzofur-4-yl)
indole and a phenylbenzofuroindole were prepared by a metal-assisted C–N intramolecular …