Protective effects of kaempferol against reactive oxygen species-induced hemolysis and its antiproliferative activity on human cancer cells

W Liao, L Chen, X Ma, R Jiao, X Li, Y Wang - European Journal of …, 2016 - Elsevier
The protective effects of kaempferol against reactive oxygen species (ROS)-induced
hemolysis and its antiproliferative activity on human cancer cells were evaluated in this …

Kaempferol suppresses cisplatin-induced apoptosis via inductions of heme oxygenase-1 and glutamate-cysteine ligase catalytic subunit in HEI-OC1 cells

SS Gao, BM Choi, XY Chen, RZ Zhu, Y Kim… - Pharmaceutical …, 2010 - Springer
Purpose The present study was undertaken to elucidate the chemoprotective mechanism of
kaempferol, which possesses anti-oxidative and anti-apoptotic properties. Methods House …

Kaempferol, a potential cytostatic and cure for inflammatory disorders

P Rajendran, T Rengarajan, N Nandakumar… - European journal of …, 2014 - Elsevier
Abstract Kaempferol (3, 5, 7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) is a
flavonoid found in many edible plants (eg, tea, broccoli, cabbage, kale, beans, endive, leek …

Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria‐dependent pathway in human osteosarcoma U‐2 OS cells

WW Huang, YJ Chiu, MJ Fan, HF Lu… - Molecular nutrition & …, 2010 - Wiley Online Library
Kaempferol is a natural flavonoid. Previous studies have reported that kaempferol has anti‐
proliferation activities and induces apoptosis in many cancer cell lines. However, there are …

Kaempferol attenuates ROS-induced hemolysis and the molecular mechanism of its induction of apoptosis on bladder cancer

P Wu, X Meng, H Zheng, Q Zeng, T Chen, W Wang… - Molecules, 2018 - mdpi.com
Bladder cancer has become the most common malignant urinary carcinoma. Studies have
shown that significant antioxidant and bladder cancer-fighting properties of several plant …

Mechanisms underlying apoptosis-inducing effects of Kaempferol in HT-29 human colon cancer cells

HS Lee, HJ Cho, R Yu, KW Lee, HS Chun… - International journal of …, 2014 - mdpi.com
We previously noted that kaempferol, a flavonol present in vegetables and fruits, reduced
cell cycle progression of HT-29 cells. To examine whether kaempferol induces apoptosis of …

Kaempferol induces apoptosis in HepG2 cells via activation of the endoplasmic reticulum stress pathway

H Guo, F Ren, LI Zhang, X Zhang… - Molecular …, 2016 - spandidos-publications.com
Kaempferol is a flavonoid compound that has gained importance due to its antitumor
properties; however, the underlying mechanisms remain to be fully understood. The present …

Kaempferol induces apoptosis in human lung non-small carcinoma cells accompanied by an induction of antioxidant enzymes

HWC Leung, CJ Lin, MJ Hour, WH Yang… - Food and Chemical …, 2007 - Elsevier
Kaempferol (3, 4′, 5, 7-tetrahydroxyflavone) is one of the most commonly found dietary
flavonols. The biological and pharmacological effects of kaempferol may depend upon its …

Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol

J Wang, X Fang, L Ge, F Cao, L Zhao, Z Wang, W Xiao - PloS one, 2018 - journals.plos.org
Kaempferol (kae) and its glycosides are widely distributed in nature and show multiple
bioactivities, yet few reports have compared them. In this paper, we report the antitumor …

Anticancer, antioxidant, ameliorative and therapeutic properties of kaempferol

M Shahbaz, M Imran, SA Alsagaby… - … Journal of Food …, 2023 - Taylor & Francis
Kaempferol, found in various plants and foods, has gained attention as a useful flavonoid
owing to its potential biological properties, including anticancer characteristics. Recent …