Clinical trials of antioxidants as cancer prevention agents: past, present, and future

M Goodman, RM Bostick, O Kucuk, DP Jones - Free Radical Biology and …, 2011 - Elsevier
The purpose of this review is to summarize the most important human clinical trials of
antioxidants as cancer prevention agents conducted to date, provide an overview of …

Role of antioxidants in the prevention of cancer

LL Bennett, S Rojas, T Seefeldt - Journal of Experimental & Clinical …, 2012 - Elsevier
This review study evaluated the literature on the role of oxidative stress in malignant
disorders and to search sources of promising antioxidants: pharmaceutical, dietary …

Dietary antioxidants and human cancer

C Borek - Integrative cancer therapies, 2004 - journals.sagepub.com
Epidemiological studies show that a high intake of anti-oxidant-rich foods is inversely related
to cancer risk. While animal and cell cultures confirm the anticancer effects of antioxidants …

Antioxidants in the treatment of cancer

K Athreya, MF Xavier - Nutrition and cancer, 2017 - Taylor & Francis
Several clinical trials have produced conflicting results regarding the benefit of antioxidants
in cancer therapy thus questioning the incorporation of these substances in standard …

Cancer chemoprevention through dietary antioxidants: progress and promise

N Khan, F Afaq, H Mukhtar - Antioxidants & redox signaling, 2008 - liebertpub.com
It is estimated that nearly one-third of all cancer deaths in the United States could be
prevented through appropriate dietary modification. Various dietary antioxidants have …

Efficacy of antioxidant supplementation in reducing primary cancer incidence and mortality: systematic review and meta-analysis

A Bardia, IM Tleyjeh, JR Cerhan, AK Sood… - Mayo Clinic …, 2008 - Elsevier
OBJECTIVE To estimate the association between antioxidant use and primary cancer
incidence and mortality and to evaluate these effects across specific antioxidant compounds …

Antioxidant vitamins and cancer

CH Hennekens - The American journal of medicine, 1994 - Elsevier
Cancer is the second leading cause of death in the United States as well as most developed
countries. Although advances in treatment have afforded tremendous benefits to large …

Redox potential of antioxidants in cancer progression and prevention

S George, H Abrahamse - Antioxidants, 2020 - mdpi.com
The benevolent and detrimental effects of antioxidants are much debated in clinical trials
and cancer research. Several antioxidant enzymes and molecules are overexpressed in …

The antioxidant conundrum in cancer

HE Seifried, SS McDonald, DE Anderson, P Greenwald… - Cancer research, 2003 - AACR
The health-related effects of interactions between reactive oxygen species (ROS) and
dietary antioxidants and the consequences of dietary antioxidant supplementation on …

Dietary carotenes, vitamin C, and vitamin E as protective antioxidants in human cancers.

T Byers, G Perry - 1992 - cabidigitallibrary.org
The role of antioxidants in protecting the human body against cancer is reviewed. Headings
include: Dietary antioxidants-theoretical roles in cancer prevention; Laboratory animal …