Antidiabetic effect of green rooibos (Aspalathus linearis) extract in cultured cells and type 2 diabetic model KK-Ay mice
R Kamakura, MJ Son, D de Beer, E Joubert, Y Miura… - Cytotechnology, 2015 - Springer
Previous studies have demonstrated antidiabetic effects for rooibos (Aspalathus linearis)
and aspalathin (ASP), one of its main polyphenols. Rooibos, an endemic plant of South …
and aspalathin (ASP), one of its main polyphenols. Rooibos, an endemic plant of South …
Aspalathin improves hyperglycemia and glucose intolerance in obese diabetic ob/ob mice
MJ Son, M Minakawa, Y Miura, K Yagasaki - European journal of nutrition, 2013 - Springer
Purpose Although several researches have demonstrated that rooibos extract has
hypoglycemic effect, the role of aspalathin, a main polyphenol in the extract, remains …
hypoglycemic effect, the role of aspalathin, a main polyphenol in the extract, remains …
Hypoglycemic effect of aspalathin, a rooibos tea component from Aspalathus linearis, in type 2 diabetic model db/db mice
A Kawano, H Nakamura, S Hata, M Minakawa, Y Miura… - Phytomedicine, 2009 - Elsevier
Effects of aspalathin, a green rooibos tea component, on glucose metabolism were studied
in vitro and in vivo. We first examined the effect of aspalathin on glucose uptake by cultured …
in vitro and in vivo. We first examined the effect of aspalathin on glucose uptake by cultured …
Acute assessment of an aspalathin-enriched green rooibos (Aspalathus linearis) extract with hypoglycemic potential
CJF Muller, E Joubert, D De Beer, M Sanderson… - Phytomedicine, 2012 - Elsevier
Rooibos, an endemic South African plant, known for its use as herbal tea, has potential as
an antidiabetic herbal product, following recent demonstration of the glucose lowering effect …
an antidiabetic herbal product, following recent demonstration of the glucose lowering effect …
Effects of Agriophyllum squarrosum extracts on glucose metabolism in KKAy mice and the associated underlying mechanisms
S Bao, S Han, W Ao - Journal of ethnopharmacology, 2019 - Elsevier
Ethnopharmacological relevance Agriophyllum squarrosum (L.) Moq. is a traditional Mongol
medicine commonly used in the treatment of diabetes. Aim of the study To examine the …
medicine commonly used in the treatment of diabetes. Aim of the study To examine the …
Therapeutic effects of an aspalathin-rich green rooibos extract, pioglitazone and atorvastatin combination therapy in diabetic db/db mice
O Patel, CJF Muller, E Joubert, B Rosenkranz, J Louw… - PloS one, 2021 - journals.plos.org
Oral therapeutics used to treat type 2 diabetes and cardiovascular disease often fail to
prevent the progression of disease and their comorbidities. Rooibos (Aspalathus linearis) …
prevent the progression of disease and their comorbidities. Rooibos (Aspalathus linearis) …
Amelioration of palmitate-induced insulin resistance in C2C12 muscle cells by rooibos (Aspalathus linearis)
Increased levels of free fatty acids (FFAs), specifically saturated free fatty acids such as
palmitate are associated with insulin resistance of muscle, fat and liver. Skeletal muscle …
palmitate are associated with insulin resistance of muscle, fat and liver. Skeletal muscle …
A beneficial role of rooibos in diabetes mellitus: a systematic review and meta-analysis
M Sasaki, N Nishida, M Shimada - Molecules, 2018 - mdpi.com
In a rapid increase in cases of diabetes mellitus worldwide, there has been interested in the
use of plant-derived polyphenols as nutraceuticals to prevent the onset and progression of …
use of plant-derived polyphenols as nutraceuticals to prevent the onset and progression of …
Myocardial glucose clearance by aspalathin treatment in young, mature, and obese insulin-resistant rats
SE Smit, R Johnson, MA Van Vuuren… - Planta …, 2018 - thieme-connect.com
Rooibos, an indigenous South African plant ingested as herbal tea, is well known for its
antioxidant effects. This in vitro study investigated aspalathin (C 21 H 24 O 11), a …
antioxidant effects. This in vitro study investigated aspalathin (C 21 H 24 O 11), a …
Agriophyllum oligosaccharides ameliorate diabetic insulin resistance through INS-R/IRS/Glut4-mediated insulin pathway in db/db mice and MIN6 cells
S Bao, X Wang, SB Cho, YL Wu, C Wei… - Frontiers in …, 2021 - frontiersin.org
We have previously reported that Agriophyllum oligosaccharides (AOS) significantly
enhance glycemic control by increasing the activation of insulin receptor (INS-R), insulin …
enhance glycemic control by increasing the activation of insulin receptor (INS-R), insulin …
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