Tailoring biomaterials for cancer immunotherapy: emerging trends and future outlook

C Wang, Y Ye, Q Hu, A Bellotti, Z Gu - Advanced materials, 2017 - Wiley Online Library
Cancer immunotherapy, as a paradigm shift in cancer treatment, has recently received
tremendous attention. The active cancer vaccination, immune checkpoint blockage (ICB) …

Advanced biomaterials for cell‐specific modulation and restore of cancer immunotherapy

S Ruan, Y Huang, M He, H Gao - Advanced Science, 2022 - Wiley Online Library
The past decade has witnessed the explosive development of cancer immunotherapies.
Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target …

Biomaterial-assisted targeted modulation of immune cells in cancer treatment

H Wang, DJ Mooney - Nature materials, 2018 - nature.com
The past decade has witnessed the accelerating development of immunotherapies for
cancer treatment. Immune checkpoint blockade therapies and chimeric antigen receptor …

Biomaterials for enhancing anti-cancer immunity

ST Koshy, DJ Mooney - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …

Engineered materials for cancer immunotherapy

AS Cheung, DJ Mooney - Nano today, 2015 - Elsevier
Immunotherapy is a promising treatment modality for cancer as it can promote specific and
durable anti-cancer responses. However, limitations to current approaches remain …

Harnessing innate immunity using biomaterials for cancer immunotherapy

DY Lee, K Huntoon, Y Wang, W Jiang… - Advanced …, 2021 - Wiley Online Library
The discovery of immune checkpoint blockade has revolutionized the field of immuno‐
oncology and established the foundation for developing various new therapies that can …

Improving cancer immunotherapy outcomes using biomaterials

S Yan, Z Luo, Z Li, Y Wang, J Tao, C Gong… - Angewandte …, 2020 - Wiley Online Library
Immunotherapy has made great strides in improving clinical outcomes in cancer treatment.
However, few patients exhibit adequate response rates for key outcome measures and …

Advances in immunotherapy delivery from implantable and injectable biomaterials

DG Leach, S Young, JD Hartgerink - Acta biomaterialia, 2019 - Elsevier
Macroscale biomaterials, such as preformed implantable scaffolds and injectable soft
materials, possess powerful synergies with anti-cancer immunotherapies. Immunotherapies …

Biomaterials to enhance antigen-specific T cell expansion for cancer immunotherapy

A Isser, NK Livingston, JP Schneck - Biomaterials, 2021 - Elsevier
T cells are often referred to as the 'guided missiles' of our immune system because of their
capacity to traffic to and accumulate at sites of infection or disease, destroy infected or …

Biomaterials tools to modulate the tumour microenvironment in immunotherapy

Y Chao, Z Liu - Nature Reviews Bioengineering, 2023 - nature.com
Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …