Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study

Y Xu, L Barregard, J Nielsen, A Gudmundsson… - Particle and fibre …, 2013 - Springer
Background Exposure to diesel exhaust causes inflammatory responses. Previous
controlled exposure studies at a concentration of 300 μg/m 3 of diesel exhaust particles …

Comparative effects of inhaled diesel exhaust and ambient fine particles on inflammation, atherosclerosis, and vascular dysfunction

C Quan, Q Sun, M Lippmann, LC Chen - Inhalation toxicology, 2010 - Taylor & Francis
Ambient air PM2. 5 (particulate matter less than 2.5 μm in diameter) has been associated
with cardiovascular diseases (CVDs), but the underlying mechanisms affecting CVDs are …

Diesel exhaust particles and airway inflammation

AJ Ghio, CB Smith, MC Madden - Current opinion in pulmonary …, 2012 - journals.lww.com
Inflammation after diesel exhaust and DEP exposure is evident at higher concentrations
only; there appears to be a threshold dose for DEPs approximating 300 μg/m 3. The lack of a …

[HTML][HTML] Effects of diesel exhaust particles on human lung epithelial cells: an in vitro study

G Mazzarella, F Ferraraccio, MV Prati, S Annunziata… - Respiratory …, 2007 - Elsevier
Atmospheric particulate matter (PM), an ingredient of urban pollution matter, is a mixture of
solid and liquid particles differing in origin, dimension and composition. There is big concern …

Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions

E Long, C Carlsten - Particle and Fibre Toxicology, 2022 - Springer
Air pollution is an issue of increasing interest due to its globally relevant impacts on
morbidity and mortality. Controlled human exposure (CHE) studies are often employed to …

The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress

AE Nel, D Diaz-Sanchez, N Li - Current opinion in pulmonary …, 2001 - journals.lww.com
We review the literature indicating that the adverse health effects of ambient particulate
matter involve the generation of oxidative stress and inflammation, as well as …

The effects of ambient particulate matter on human alveolar macrophage oxidative and inflammatory responses

K Sawyer, S Mundandhara, AJ Ghio… - Journal of Toxicology …, 2009 - Taylor & Francis
Epidemiologic and occupational studies demonstrated that ambient particulate matter (PM)
and diesel exhaust particles (DEP) exert deleterious effects on human cardiopulmonary …

Use of proteomics to demonstrate a hierarchical oxidative stress response to diesel exhaust particle chemicals in a macrophage cell line

GG Xiao, M Wang, N Li, JA Loo, AE Nel - Journal of Biological Chemistry, 2003 - ASBMB
Epidemiological studies demonstrate an association between short term exposure to
ambient particulate matter (PM) and cardiorespiratory morbidity and mortality. Although the …

Particulate matter in new technology diesel exhaust (NTDE) is quantitatively and qualitatively very different from that found in traditional diesel exhaust (TDE)

TW Hesterberg, CM Long, SN Sax… - Journal of the Air & …, 2011 - Taylor & Francis
Diesel exhaust (DE) characteristic of pre-1988 engines is classified as a “probable” human
carcinogen (Group 2A) by the International Agency for Research on Cancer (IARC), and the …

Diesel exhaust particulate (DEP) and nanoparticle exposures: what do DEP human clinical studies tell us about potential human health hazards of nanoparticles?

TW Hesterberg, CM Long, CA Lapin… - Inhalation …, 2010 - Taylor & Francis
Engineered nanoparticles (ENPs) are increasingly tested in cellular and laboratory-animal
experiments for hazard potential, but there is a lack of health effects data for humans …