Inhaled Diesel Engine Emissions Reduce Bacterial Clearance and Exacerbate Lung Disease to Pseudomonas aeruginosa Infection In Vivo

KS Harrod, RJ Jaramillo, JA Berger… - Toxicological …, 2005 - academic.oup.com
Despite experimental evidence supporting an adverse role for air pollution in models of
human disease, little has been done in the way of assessing the health effects of inhalation …

Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

J Ji, S Upadhyay, X Xiong, M Malmlöf… - Particle and fibre …, 2018 - Springer
Background Diesel exhaust particles (DEP) are a major component of outdoor air pollution.
DEP mediated pulmonary effects are plausibly linked to inflammatory and oxidative stress …

[HTML][HTML] Long-term effects of diesel exhaust particles on airway inflammation and remodeling in a mouse model

BG Kim, PH Lee, SH Lee, YE Kim, MY Shin… - Allergy, asthma & …, 2016 - ncbi.nlm.nih.gov
Purpose Diesel exhaust particles (DEPs) can induce and trigger airway
hyperresponsiveness (AHR) and inflammation. The aim of this study was to investigate the …

Health effects of exposure to diesel exhaust particles

RO McClellan - Annual review of pharmacology and toxicology, 1987 - annualreviews.org
The health effects of diesel exhaust (DE) have been a focus of intensive research during the
last decade. Increased use of diesel engines in light-duty passenger cars and vans …

Chemicals in diesel exhaust particles generate reactive oxygen radicals and induce apoptosis in macrophages

TS Hiura, MP Kaszubowski, N Li… - The Journal of …, 1999 - journals.aai.org
There is increasing evidence that particulate air pollutants, such as diesel exhaust particles
(DEP), potentiate chronic inflammatory processes as well as acute symptomatic responses …

Differential effects of the particle core and organic extract of diesel exhaust particles

AI Totlandsdal, JI Herseth, AK Bølling, A Kubátová… - Toxicology letters, 2012 - Elsevier
Exposure to diesel engine exhaust particles (DEPs), representing a complex and variable
mixture of components, has been associated with lung disease and induction of pro …

Acute cardiovascular and inflammatory toxicity induced by inhalation of diesel and biodiesel exhaust particles

JM Brito, L Belotti, AC Toledo… - Toxicological …, 2010 - academic.oup.com
Abstract Analysis of fuel emissions is crucial for understanding the pathogenesis of mortality
because of air pollution. The objective of this study is to assess cardiovascular and …

From particles to patients: oxidative stress and the cardiovascular effects of air pollution

MR Miller, CA Shaw, JP Langrish - Future cardiology, 2012 - Future Medicine
Air pollution, especially airborne particulate matter (PM), is associated with an increase in
both morbidity and mortality from cardiovascular disease, although the underlying …

Pathogenic role of air pollution particulate matter in cardiometabolic disease: evidence from mice and humans

T Marchini, A Zirlik, D Wolf - Antioxidants & redox signaling, 2020 - liebertpub.com
Significance: Air pollution is a considerable global threat to human health that dramatically
increases the risk for cardiovascular pathologies, such as atherosclerosis, myocardial …

Effects of diesel exhaust particles (DEP), carbon black, and silica on macrophage responses to lipopolysaccharide: evidence of DEP suppression of macrophage …

HM Yang, MW Barger, V Castranova… - Journal of Toxicology …, 1999 - Taylor & Francis
The effects of diesel exhaust particle (DEP) exposure on alveolar macrophage (AM)
response to ex vivo and in vivo lipopolysaccharide (LPS) challenge were determined by …