AIM: To determine the effects of genetic variants associated with gallstone formation and
capsaicin (a pungent component of chili pepper) metabolism on the risk of gallbladder …

BACKGROUND & AIMS: Genome-wide association studies have mapped loci that are
associated with serum levels of bilirubin. Bilirubin is a major component of gallstones so we …

Background & Aims A genome-wide association study (GWAS) of 280 cases identified the
hepatic cholesterol transporter ABCG8 as a locus associated with risk for gallstone disease …

Gallbladder carcinoma is a highly aggressive cancer with female predominance.
Interindividual differences in the effectiveness of the activation/detoxification of …

Background and Aims Gallbladder cancer (GBC) is a neglected disease with substantial
geographical variability: Chile shows the highest incidence worldwide, while GBC is …

Abstract Background and Aim: Gallbladder carcinoma (GBC) usually arises in the
background of gallstone disease which may be causatively related to decreased gallbladder …

Objectives: The objectives for this study were to examine the associations between
metabolic biomarkers of obesity including insulin resistance, vascular dysfunction, systemic …

A CYP1A1 polymorphism has been associated with an increased risk for gallbladder cancer
(GBC) in Japanesewomen. However, genetic risk factors for GBC in Hungary, where the …

Background In this study, we evaluated the association between these polymorphisms and
gallstone disease using meta-analysis and compared the hepatic ABCG5/G8 mRNA …

Background Gallstone disease is one of the most common digestive disorders, affecting
more than 30 million Americans. Previous twin studies suggest a heritability of 25% for …