Immune-checkpoint inhibition for resectable non-small-cell lung cancer—Opportunities and challenges

G Mountzios, J Remon, LEL Hendriks… - Nature Reviews …, 2023 - nature.com
Therapeutic strategies harnessing the immune system to eliminate tumour cells have been
successfully used for several cancer types, including in patients with advanced-stage non …

[HTML][HTML] Incorporating immune-checkpoint inhibitors into systemic therapy of NSCLC

S Champiat, E Ileana, G Giaccone, B Besse… - Journal of thoracic …, 2014 - Elsevier
Despite current therapeutic options metastatic non–small-cell lung cancer (NSCLC) remains
incurable. Targeted therapies have opened new opportunities for several molecular …

[HTML][HTML] Immune checkpoint inhibitors in non-small cell lung cancer: progress, challenges, and prospects

S Tang, C Qin, H Hu, T Liu, Y He, H Guo, H Yan… - Cells, 2022 - mdpi.com
Non-small cell lung cancer is one of the most common types of malignances worldwide and
the main cause of cancer-related deaths. Current treatment for NSCLC is based on surgical …

[HTML][HTML] Role and impact of immune checkpoint inhibitors in neoadjuvant treatment for NSCLC

A Friedlaender, J Naidoo, GL Banna, G Metro… - Cancer treatment …, 2022 - Elsevier
In the last decade, immune-checkpoint inhibitors (ICIs) have become the backbone of
therapy in advanced, non-oncogene driven, non-small cell lung cancer (NSCLC). More …

The evolving immuno-oncology landscape in advanced lung cancer: first-line treatment of non-small cell lung cancer

JL Low, RJ Walsh, Y Ang, G Chan… - … advances in medical …, 2019 - journals.sagepub.com
Lung cancer is the most common cancer and leading cause of cancer death. While targeted
therapies have redefined treatment options for non-small cell lung carcinoma (NSCLC) with …

Neoadjuvant immunotherapy for non–small cell lung cancer: State of the art

J Kang, C Zhang, WZ Zhong - Cancer Communications, 2021 - Wiley Online Library
Lung cancer mortality has decreased over the past decade and can be partly attributed to
advances in targeted therapy and immunotherapy. Immune checkpoint inhibitors (ICIs) have …

Immune checkpoint inhibitors in advanced non–small cell lung cancer

HI Assi, AO Kamphorst, NM Moukalled… - Cancer, 2018 - Wiley Online Library
The emergence of immune checkpoint inhibitors for the treatment of cancer has led to major
changes to the therapeutic landscape of lung cancer. Improvements in overall survival …

[HTML][HTML] Clinically relevant prognostic and predictive markers for immune-checkpoint-inhibitor (ICI) therapy in non-small cell lung cancer (NSCLC)

WM Brueckl, JH Ficker, G Zeitler - BMC cancer, 2020 - Springer
Background Immune checkpoint inhibitors (ICI) either alone or in combination with
chemotherapy have expanded our choice of agents for the palliative treatment of non-small …

[HTML][HTML] Neoadjuvant immune checkpoint inhibitors in resectable non-small-cell lung cancer: a systematic review

EB Ulas, C Dickhoff, FL Schneiders, S Senan, I Bahce - Esmo Open, 2021 - Elsevier
Background The neoadjuvant use of immune checkpoint inhibitors (ICIs) in resectable non-
small-cell lung cancer (NSCLC) is currently an area of active ongoing research. The place of …

[HTML][HTML] Neoadjuvant and adjuvant immunotherapy: opening new horizons for patients with early-stage non-small cell lung cancer

R Bai, L Li, X Chen, N Chen, W Song, J Cui - Frontiers in Oncology, 2020 - frontiersin.org
Lung cancer is the most common malignant tumor with the highest mortality, and about 84%
are non-small cell lung cancer (NSCLC). However, only a small proportion of patients with …