Diuretics have been used successfully as antihypertensive drugs for over 30 years. In 1957,
chlorothiazide was introduced into clinical trials to treat hypertensive patients (H ollander …

Diuretics were the first effective oral agents for treating hypertension. They have proven to
be safe and effective. Recently, they have been scrutinized as possibly being responsible for …

Diuretics have traditionally been the keystone of antihypertensive therapy. A variety of
clinical trials, designed to examine the benefit of blood pressure reduction in decreasing …

With 30 years of experience, it is possible to claim that diuretics are well tolerated
antihypertensive drugs Educing a significant decrease in systolic and diastolic blood …

The antihypertensive effect of diuretics is relatively mild and depends on the initial blood
pressure level. On average, a decrease in systolic and diastolic pressures of about 10% can …

Diuretics have been and will likely remain the most widely used agent for the initial drug
therapy of primary hypertension. The mode of their antihypertensive action is reviewed …

Diuretics are as effective as newer treatments in hypertension and they still remain drugs of
first choice. This Drug review considers their mode of action and properties, followed by …

Thiazide-type diuretics are one of the most important antihypertensive classes in the
management of hypertension. They are one of the preferred antihypertensive classes for …

Diuretics are as effective as newer treatments in hypertension and they still remain drugs of
first choice. This Drug Review considers their mode of action and properties, followed by …

Recent progress in antihypertensive therapy has widened the selection of drugs, and large
clinical trials have attracted attention to newer classes of antihypertensives. Consequently …