Extracellular matrix in kidney fibrosis: more than just a scaffold
Kidney fibrosis is the common histological end-point of progressive, chronic kidney diseases
(CKDs) regardless of the underlying etiology. The hallmark of renal fibrosis, similar to all …
(CKDs) regardless of the underlying etiology. The hallmark of renal fibrosis, similar to all …
The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis?
F Genovese, AA Manresa, DJ Leeming… - Fibrogenesis & tissue …, 2014 - Springer
Interstitial fibrosis is the common endpoint of end-stage chronic kidney disease (CKD)
leading to kidney failure. The clinical course of many renal diseases, and thereby of CKD, is …
leading to kidney failure. The clinical course of many renal diseases, and thereby of CKD, is …
Interplay between extracellular matrix components and cellular and molecular mechanisms in kidney fibrosis
S Rayego-Mateos, S Campillo… - Clinical …, 2021 - portlandpress.com
Chronic kidney disease (CKD) is characterized by pathological accumulation of extracellular
matrix (ECM) proteins in renal structures. Tubulointerstitial fibrosis is observed in glomerular …
matrix (ECM) proteins in renal structures. Tubulointerstitial fibrosis is observed in glomerular …
The fibrogenic niche in kidney fibrosis: components and mechanisms
Kidney fibrosis, characterized by excessive deposition of extracellular matrix (ECM) that
leads to tissue scarring, is the final common outcome of a wide variety of chronic kidney …
leads to tissue scarring, is the final common outcome of a wide variety of chronic kidney …
Epithelial to mesenchymal transition as a biomarker in renal fibrosis: are we ready for the bedside?
P Galichon, A Hertig - Fibrogenesis & tissue repair, 2011 - Springer
Over the past two decades, the concept of the epithelial to mesenchymal transition (EMT)
has been imported from embryology and oncology to fibrosis, particularly in the kidney. This …
has been imported from embryology and oncology to fibrosis, particularly in the kidney. This …
Epithelial to mesenchymal transition (EMT) and endothelial to mesenchymal transition (EndMT): role and implications in kidney fibrosis
AS Cruz-Solbes, K Youker - Kidney development and disease, 2017 - Springer
Tubulointerstitial injury is one of the hallmarks of renal disease. In particular, interstitial
fibrosis has a prominent role in the development and progression of kidney injury. Collagen …
fibrosis has a prominent role in the development and progression of kidney injury. Collagen …
Partial epithelial-to-mesenchymal transition and other new mechanisms of kidney fibrosis
Kidney fibrosis is the unavoidable consequence of chronic kidney disease irrespective of the
primary underlying insult. It is a complex phenomenon governed by the interplay between …
primary underlying insult. It is a complex phenomenon governed by the interplay between …
Proteomic landscape of the extracellular matrix in the fibrotic kidney
L Li, M He, X Tang, J Huang, J Li, X Hong, H Fu… - Kidney International, 2023 - Elsevier
The extracellular matrix (ECM) is a complex three-dimensional network of proteins
surrounding cells, forming a niche that controls cell adhesion, proliferation, migration and …
surrounding cells, forming a niche that controls cell adhesion, proliferation, migration and …
Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease
J He, Y Xu, D Koya, K Kanasaki - Clinical and experimental nephrology, 2013 - Springer
All types of progressive chronic kidney disease (CKD) inevitably induce renal fibrosis, the
hallmark of which is the activation and accumulation of a large number of matrix-producing …
hallmark of which is the activation and accumulation of a large number of matrix-producing …
New insights into epithelial-mesenchymal transition in kidney fibrosis
Y Liu - Journal of the American Society of Nephrology, 2010 - journals.lww.com
Abstract Epithelial-mesenchymal transition (EMT), a process by which differentiated
epithelial cells undergo a phenotypic conversion that gives rise to the matrix-producing …
epithelial cells undergo a phenotypic conversion that gives rise to the matrix-producing …
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