Hyperinsulinemic hypoglycemia–the molecular mechanisms
A Nessa, SA Rahman, K Hussain - Frontiers in endocrinology, 2016 - frontiersin.org
Under normal physiological conditions, pancreatic β-cells secrete insulin to maintain fasting
blood glucose levels in the range 3.5–5.5 mmol/L. In hyperinsulinemic hypoglycemia (HH) …
blood glucose levels in the range 3.5–5.5 mmol/L. In hyperinsulinemic hypoglycemia (HH) …
Congenital hypoglycemia disorders: new aspects of etiology, diagnosis, treatment and outcomes: highlights of the proceedings of the congenital hypoglycemia …
DD De Leon, CA Stanley - Pediatric Diabetes, 2017 - Wiley Online Library
Hypoglycemia continues to be an important cause of morbidity in neonates and children.
Prompt diagnosis and management of the underlying hypoglycemia disorder is critical for …
Prompt diagnosis and management of the underlying hypoglycemia disorder is critical for …
Hyperinsulinaemic hypoglycaemia
Hyperinsulinaemic hypoglycaemia (HH) occurs as a consequence of unregulated insulin
secretion from pancreatic β cells. In the newborn period it is the most common cause of …
secretion from pancreatic β cells. In the newborn period it is the most common cause of …
Hyperinsulinism in developmental syndromes
Hyperinsulinism is a cause of recurrent and severe hypoglycaemia in the newborn and
infancy period. Several developmental genetic syndromes are associated with …
infancy period. Several developmental genetic syndromes are associated with …
Hyperinsulinemic hypoglycemia in children and adolescents: recent advances in understanding of pathophysiology and management
M Gϋemes, SA Rahman, RR Kapoor… - Reviews in Endocrine …, 2020 - Springer
Hyperinsulinemic hypoglycemia (HH) is characterized by unregulated insulin release,
leading to persistently low blood glucose concentrations with lack of alternative fuels, which …
leading to persistently low blood glucose concentrations with lack of alternative fuels, which …
The contribution of rapid KATP channel gene mutation analysis to the clinical management of children with congenital hyperinsulinism
I Banerjee, M Skae, SE Flanagan… - European journal of …, 2011 - academic.oup.com
Objective In children with congenital hyperinsulinism (CHI), KATP channel genes (ABCC8
and KCNJ11) can be screened rapidly for potential pathogenic mutations. We aimed to …
and KCNJ11) can be screened rapidly for potential pathogenic mutations. We aimed to …
Hyperinsulinism in infancy and childhood: when an insulin level is not always enough
AA Palladino, MJ Bennett, CA Stanley - Bioquimia, 2009 - medigraphic.com
Background: Hypoglycemia in infants and children can lead to seizures, developmental
delay, and permanent brain damage. Hyperinsulinism (HI) is the most common cause of …
delay, and permanent brain damage. Hyperinsulinism (HI) is the most common cause of …