Environmental Regulation of the Heart: The Role of Non-Coding RNA and Epigenetics in Influencing Mitochondrial and Cellular Health

QA Hathaway - 2019 - researchrepository.wvu.edu
The mitochondrion, a small but ubiquitously distributed organelle in the cell, continues to be
the focus of many disease pathogeneses, tissue and organ dysfunctions, and other …

[PDF][PDF] Specific Aim 3

RNA Non-Coding - … Regulation of the Heart: The Role …, 2019 - researchrepository.wvu.edu
Specific Aim 3 Page 271 252 Chapter 4: Specific Aim 3 The Mitochondrial Regulatory Network:
Subcellular Localization of Non-Coding RNA in the Heart Quincy A. Hathaway1, 2, Andrew D …

Loss of Functional Non‐Coding RNA Diversity in Diabetic Cardiac Mitochondria

AD Taylor, QA Hathaway, A Kunovac… - The FASEB …, 2020 - Wiley Online Library
Individuals with diabetes mellitus are predisposed to cardiovascular complications, but no
effective predictive or therapeutic measure is in place to prevent these morbidities …

[HTML][HTML] Integrative Cardiovascular Physiology and Pathophysiology: MitoQ regulates redox-related noncoding RNAs to preserve mitochondrial network integrity in …

S Kim, J Song, P Ernst, MN Latimer, CM Ha… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Evidence suggests that mitochondrial network integrity is impaired in cardiomyocytes from
failing hearts. While oxidative stress has been implicated in heart failure (HF)-associated …

Mitochondrial noncoding RNA-regulatory network in cardiovascular disease

A Jusic, Y Devaux… - Basic research in …, 2020 - Springer
Mitochondrial function and integrity are vital for the maintenance of cellular homeostasis,
particularly in high-energy demanding cells. Cardiomyocytes have a large number of …

Cardiac mitochondrial dynamics: miR-mediated regulation during cardiac injury

A Sivakumar, R Subbiah, R Balakrishnan… - Journal of Molecular and …, 2017 - Elsevier
Mitochondrial integrity is indispensable for cardiac health. With the advent of modern
imaging technologies, mitochondrial motility and dynamics within the cell are extensively …

miRNA-378a as a key regulator of cardiovascular health following engineered nanomaterial inhalation exposure

QA Hathaway, AJ Durr, DL Shepherd, MV Pinti… - …, 2019 - Taylor & Francis
Nano-titanium dioxide (nano-TiO2), though one of the most utilized and produced
engineered nanomaterials (ENMs), diminishes cardiovascular function through …

[HTML][HTML] The mitoscriptome in aging and disease

R Raju, B Jian, W Hubbard, I Chaudry - Aging and disease, 2011 - ncbi.nlm.nih.gov
Mitochondria are the major sites where energy is produced in the cell. Functions of organs
such as the heart which has high energy demand are seriously affected by dysfunction of …

MitoQ regulates redox-related noncoding RNAs to preserve mitochondrial network integrity in pressure-overload heart failure

S Kim, J Song, P Ernst, MN Latimer… - American Journal …, 2020 - journals.physiology.org
Evidence suggests that mitochondrial network integrity is impaired in cardiomyocytes from
failing hearts. While oxidative stress has been implicated in heart failure (HF)-associated …

Integrated transcriptome analysis across mitochondrial disease etiologies and tissues improves understanding of common cellular adaptations to respiratory chain …

Z Zhang, MJ Falk - The international journal of biochemistry & cell biology, 2014 - Elsevier
Mitochondrial diseases are heterogeneous, multi-systemic disorders for which mechanistic
understanding is limited. To investigate common downstream effects of primary respiratory …