Anabolic and antiresorptive therapy for osteoporosis: combination and sequential approaches

F Cosman - Current osteoporosis reports, 2014 - Springer
Abstract In the recent Bone Key Reports review, it was noted that combinations of anabolic
and antiresorptive agents have potential to improve bone density and bone strength more …

[HTML][HTML] Combination therapy for osteoporosis: a reappraisal

F Cosman - BoneKEy Reports, 2014 - ncbi.nlm.nih.gov
Combinations of anabolic and antiresorptive agents have potential to improve bone density
and bone strength more than either agent alone. A large number of relatively small clinical …

Treatment sequence matters: anabolic and antiresorptive therapy for osteoporosis

F Cosman, JW Nieves… - Journal of bone and …, 2017 - academic.oup.com
The effects of anabolic medications (teriparatide [TPTD] and parathyroid hormone [PTH])
differ in patients who have received recent treatment with potent antiresorptives. This …

Optimizing sequential and combined anabolic and antiresorptive osteoporosis therapy

BZ Leder - Journal of Bone and Mineral Research Plus, 2018 - academic.oup.com
As osteoporosis therapy options have expanded, and clinical guidelines have begun to
embrace the concept of limited treatment courses and “drug holidays,” the choices that …

Anabolic therapy and optimal treatment sequences for patients with osteoporosis at high risk for fracture

F Cosman - Endocrine Practice, 2020 - Elsevier
Objective: Provide an update regarding anabolic medications for osteoporosis, which are
often considered to be the last resort for patients with osteoporosis, after multiple fractures …

Emerging insights into the comparative effectiveness of anabolic therapies for osteoporosis

EG Estell, CJ Rosen - Nature Reviews Endocrinology, 2021 - nature.com
Over the past three decades, the mainstay of treatment for osteoporosis has been
antiresorptive agents (such as bisphosphonates), which have been effective with continued …

Overview of treatment approaches to osteoporosis

BL Langdahl - British Journal of pharmacology, 2021 - Wiley Online Library
Efficient therapies are available for the treatment of osteoporosis. Anti‐resorptive therapies,
including bisphosphonates and denosumab, increase bone mineral density (BMD) and …

[PDF][PDF] Treatment of osteoporosis: unmet needs and emerging solutions

BL Langdahl, JD Andersen - Journal of Bone Metabolism, 2018 - synapse.koreamed.org
Efficient therapies are available for the treatment of osteoporosis, however, there are still
unmet needs. Anti-resorptive therapies only increase bone mineral density to a certain …

Combination/sequential therapies for anabolic and antiresorptive skeletal agents for osteoporosis

JP Bilezikian, MR Rubin - Current Osteoporosis Reports, 2006 - Springer
In this paper, we focus upon the use of anabolic skeletal therapy for the treatment of
postmenopausal and other forms of osteoporosis. The only anabolic skeletal agent currently …

[HTML][HTML] Osteoporosis: Spotlight on current approaches to pharmacological treatment

D Sindel - Turkish journal of physical medicine and rehabilitation, 2023 - ncbi.nlm.nih.gov
Despite the availability of safe and effective anti-osteoporosis treatments, osteoporosis
continues to be undertreated. The increase in fragility fractures, which is the main clinical …