Objective The incidence of inappropriate and excessive empirical antibiotic therapy is
unclear. The aim of this study was to determine the prevalence of different empirical …

Background Empiric antibiotic use among hospitalized adults in the United States (US) is
largely undescribed. Identifying factors associated with broad-spectrum empiric therapy may …

Background The rapid global spread of multi-resistant bacteria and loss of antibiotic
effectiveness increases the risk of initial inappropriate antibiotic therapy (IAT) and poses a …

Background Several strategies to optimise the use of antibiotics have been developed. Most
of these interventions can be classified as educational or restrictive. Restrictive measures …

Few studies describe the frequency of antibiotic regimen modification behaviors in the acute
care setting. We sought to ascertain patient and treatment characteristics, details of regimen …

Summary Background Approximately 20–50% of antimicrobial therapy in hospitalized
patients is considered inappropriate, which may be associated with increased morbidity and …

Abstract Background Empiric Gram-negative antibiotics are frequently changed in response
to new information. To inform antibiotic stewardship, we sought to identify predictors of …

Background Modification of empirical antimicrobials when warranted by culture results or
clinical signs is recommended to control antimicrobial overuse and resistance. We aimed to …

Background Assessment of antimicrobial use places an emphasis on therapeutic aspects of
infected patients. Our aim was to determine the risk factors for unnecessary antibiotic …

Background: This study aims to evaluate the antimicrobial prescribing practices in hospital
settings in Italy, focusing on the appropriateness of antibiotic use. Methods: This study was …