[HTML][HTML] HAM/TSP-derived HTLV-1-infected T cell lines promote morphological and functional changes in human astrocytes cell lines: possible role in the enhanced T …

ES Gudo, SD Silva-Barbosa, L Linhares-Lacerda… - Virology Journal, 2015 - Springer
Background The mechanisms through which HTLV-1 leads to and maintains damage in the
central nervous system of patients undergoing HTLV-1 associated myelopathy/tropical …

HTLV-1 induces a Th1-like state in CD4+ CCR4+ T cells that produces an inflammatory positive feedback loop via astrocytes in HAM/TSP

Y Yamano, A Coler-Reilly - Journal of neuroimmunology, 2017 - Elsevier
The main feature of Human T-lymphotropic virus type I (HTLV-1)-associated
myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis is a virus-induced …

[HTML][HTML] Human T-lymphotropic virus type 1 (HTLV-1) and cellular immune response in HTLV-1-associated myelopathy/tropical spastic paraparesis

S Nozuma, R Kubota, S Jacobson - Journal of NeuroVirology, 2020 - Springer
Human T-lymphotropic virus type 1 (HTLV-1) is associated with adult T cell
leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis …

Immunopathogenesis of HTLV-1-assoaciated myelopathy/tropical spastic paraparesis (HAM/TSP)

HT Fuzii, GA da Silva Dias, RJS de Barros, LFM Falcão… - Life sciences, 2014 - Elsevier
Human T-cell lymphotropic virus type 1 (HTLV-1) is associated with adult T-cell
leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis …

Visualization of HTLV-1–specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1–associated myelopathy/tropical spastic Paraparesis

E Matsuura, R Kubota, Y Tanaka… - … of Neuropathology & …, 2015 - academic.oup.com
Activated human T-lymphotropic virus type-1 (HTLV-1)–specific CD8-positive cytotoxic T
lymphocytes (CTLs) are markedly increased in the periphery of patients with HTLV-1 …

A new hypothesis for the pathogenesis of Human T-lymphotropic virus type 1 associated myelopathy/tropical spastic paraparesis

AJ Mosley, CRM Bangham - Bioscience Hypotheses, 2009 - Elsevier
The exogenous, human retrovirus Human T-lymphotropic virus type 1 (HTLV-1) results in a
highly dynamic persistent infection. HTLV-1 usually causes an asymptomatic infection but a …

Neuroimmunological aspects of human T cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis

M Saito - Journal of neurovirology, 2014 - Springer
Human T cell leukemia virus type 1 (HTLV-1) is a replicationcompetent human retrovirus
associated with two distinct types of disease: a malignancy of mature CD4+ T cells called …

Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha

R Szymocha, H Akaoka, M Dutuit, C Malcus… - Journal of …, 2000 - Am Soc Microbiol
Human T-cell lymphotropic virus type 1 (HTLV-1) is the causative agent of a chronic
progressive myelopathy called tropical spastic paraparesis/HTLV-1-associated myelopathy …

Pathogenesis of human T‐lymphotropic virus type 1‐associated myelopathy/tropical spastic paraparesis

R Kubota - Clinical and Experimental Neuroimmunology, 2017 - Wiley Online Library
Human T‐lymphotropic virus type 1 (HTLV‐1) is a human retrovirus that preferentially infects
CD 4+ lymphocytes in vivo. The virus causes a hematological malignancy known as adult T …

HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP): a chronic progressive neurologic disease associated with immunologically mediated damage …

MC Levin, S Jacobson - Journal of neurovirology, 1997 - Taylor & Francis
This review examines information on clinical, pathological and immunological events in the
slowly progressive neurologic disorder associated with the human T lymphotropic virus type …