[HTML][HTML] Placental mitochondrial dysfunction with metabolic diseases: Therapeutic approaches
JF Hebert, L Myatt - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2021 - Elsevier
Both obesity and gestational diabetes mellitus (GDM) lead to poor maternal and fetal
outcomes, including pregnancy complications, fetal growth issues, stillbirth, and …
outcomes, including pregnancy complications, fetal growth issues, stillbirth, and …
[HTML][HTML] Obesity-exposed oocytes accumulate and transmit damaged mitochondria due to an inability to activate mitophagy
AL Boudoures, J Saben, A Drury, S Scheaffer… - Developmental …, 2017 - Elsevier
Mitochondria are the most prominent organelle in the oocyte. Somatic cells maintain a
healthy population of mitochondria by degrading damaged mitochondria via mitophagy, a …
healthy population of mitochondria by degrading damaged mitochondria via mitophagy, a …
Mitochondria in early development: linking the microenvironment, metabolism and the epigenome
AJ Harvey - Reproduction, 2019 - rep.bioscientifica.com
Mitochondria, originally of bacterial origin, are highly dynamic organelles that have evolved
a symbiotic relationship within eukaryotic cells. Mitochondria undergo dynamic, stage …
a symbiotic relationship within eukaryotic cells. Mitochondria undergo dynamic, stage …
Placental mitochondria and reactive oxygen species in the physiology and pathophysiology of pregnancy
Mitochondria are central to cell function. The placenta forms the interface between maternal
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …
[HTML][HTML] Aging and the environment affect gamete and embryo potential: can we intervene?
DR Meldrum, RF Casper, A Diez-Juan, C Simon… - Fertility and sterility, 2016 - Elsevier
Optimal maturation of the oocyte depends on its environment and determines embryo
competence, because the embryonic genome is not active until the cleavage stage and new …
competence, because the embryonic genome is not active until the cleavage stage and new …