WHO has declared obesity to be a global epidemic. Obesity management strategies mainly
target behavioural components of the disorder, but are only marginally effective. A …

Obesity and type 2 diabetes mellitus (T2D) are global pandemics. Worldwide, the
prevalence of obesity has nearly tripled since 1975 and the prevalence of T2D has almost …

Immunometabolism is an emerging field of investigation at the interface between the
historically distinct disciplines of immunology and metabolism. Accelerating interest in this …

This paper considers the argument for obesity as a chronic relapsing disease process.
Obesity is viewed from an epidemiological model, with an agent affecting the host and …

Infections are a major complication of obesity, but the mechanisms responsible for impaired
defense against microbes are not well understood. Here, we found that adipocyte …

Obesity is associated with a wide range of complications, including type 2 diabetes mellitus,
cardiovascular disease, hypertension and nonalcoholic fatty liver disease. Obesity also …

Obesity is a health concern that is recognized as a critical factor for vulnerability to influenza
A/pdmH1N1 virus infection, with epidemiological and clinical impacts. In humans, obesity …

Research examining immune function during obesity suggests that excessive adiposity is
linked to impaired immune responses leading to pathology. The deleterious effects of …

The rapid increase in obesity prevalence in the United States in the last 20 years is
unprecedented and not well explained. Here, we explore a hypothesis that the obesity …

Compelling epidemiological evidence reveals a strong association between being
overweight or obese and the risk of developing autoimmune diseases. From an …