A framework for identification of infections that contribute to human obesity
NV Dhurandhar - The Lancet infectious diseases, 2011 - thelancet.com
WHO has declared obesity to be a global epidemic. Obesity management strategies mainly
target behavioural components of the disorder, but are only marginally effective. A …
target behavioural components of the disorder, but are only marginally effective. A …
Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality
LM Frydrych, G Bian, DE O'Lone… - Journal of leukocyte …, 2018 - academic.oup.com
Obesity and type 2 diabetes mellitus (T2D) are global pandemics. Worldwide, the
prevalence of obesity has nearly tripled since 1975 and the prevalence of T2D has almost …
prevalence of obesity has nearly tripled since 1975 and the prevalence of T2D has almost …
Immunometabolism: an emerging frontier
D Mathis, SE Shoelson - Nature Reviews. Immunology, 2011 - nature.com
Immunometabolism is an emerging field of investigation at the interface between the
historically distinct disciplines of immunology and metabolism. Accelerating interest in this …
historically distinct disciplines of immunology and metabolism. Accelerating interest in this …
Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation
GA Bray, KK Kim, JPH Wilding… - Obesity …, 2017 - Wiley Online Library
This paper considers the argument for obesity as a chronic relapsing disease process.
Obesity is viewed from an epidemiological model, with an agent affecting the host and …
Obesity is viewed from an epidemiological model, with an agent affecting the host and …
Diet-induced obesity promotes infection by impairment of the innate antimicrobial defense function of dermal adipocyte progenitors
L Zhang, CF Guerrero-Juarez, SX Chen… - Science translational …, 2021 - science.org
Infections are a major complication of obesity, but the mechanisms responsible for impaired
defense against microbes are not well understood. Here, we found that adipocyte …
defense against microbes are not well understood. Here, we found that adipocyte …
Emerging mechanisms of obesity-associated immune dysfunction
SR Shaikh, MA Beck, Y Alwarawrah… - Nature Reviews …, 2024 - nature.com
Obesity is associated with a wide range of complications, including type 2 diabetes mellitus,
cardiovascular disease, hypertension and nonalcoholic fatty liver disease. Obesity also …
cardiovascular disease, hypertension and nonalcoholic fatty liver disease. Obesity also …
Immunity to influenza: impact of obesity
SA Rojas-Osornio, TR Cruz-Hernández… - Obesity Research & …, 2019 - Elsevier
Obesity is a health concern that is recognized as a critical factor for vulnerability to influenza
A/pdmH1N1 virus infection, with epidemiological and clinical impacts. In humans, obesity …
A/pdmH1N1 virus infection, with epidemiological and clinical impacts. In humans, obesity …
Influence of physical activity and nutrition on obesity‐related immune function
CJ Huang, MC Zourdos, E Jo… - The scientific world …, 2013 - Wiley Online Library
Research examining immune function during obesity suggests that excessive adiposity is
linked to impaired immune responses leading to pathology. The deleterious effects of …
linked to impaired immune responses leading to pathology. The deleterious effects of …
[HTML][HTML] Obesity in the United States–dysbiosis from exposure to low-dose antibiotics?
LW Riley, E Raphael, E Faerstein - Frontiers in public health, 2013 - frontiersin.org
The rapid increase in obesity prevalence in the United States in the last 20 years is
unprecedented and not well explained. Here, we explore a hypothesis that the obesity …
unprecedented and not well explained. Here, we explore a hypothesis that the obesity …
The link between obesity and autoimmunity
G Matarese - Science, 2023 - science.org
Compelling epidemiological evidence reveals a strong association between being
overweight or obese and the risk of developing autoimmune diseases. From an …
overweight or obese and the risk of developing autoimmune diseases. From an …