The adipocyte and its secretory products have been implicated in a vast array of
physiological processes. Work in many laboratories is focusing on the specific contributions …

Microbiota, Antibiotics, and Obesity | New England Journal of Medicine Skip to main content The
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Adipose tissue provides the body with a storage depot of nutrients that is drained during
times of starvation and replenished when food sources are abundant. As such, it is the …

Over the past decades, the relationship between the immune system and metabolism has
become a major research focus. In this arena of immunometabolism the capacity of adipose …

The innate immune system is a prewired set of cellular and humoral components that has
developed to sense perturbations in normal physiology and trigger responses to restore the …

There is a growing public health crisis that is global in scope, and it isn't another emerging
infectious disease. It concerns being overweight and the adverse health consequences of …

There is a tightly regulated interaction, which is well‐conserved in evolution, between the
metabolic and immune systems that is deranged in states of over‐or under‐nutrition …

The immune responses to many infections have long been known to share features with
autoimmune responses. In particular, both types of response are typified by the enhanced …

Using an epidemiologic model of the interactions between environmental agents and
human hosts to explain obesity, we explored food, medications, physical inactivity, toxins …

Obesity is associated with chronic low‐grade inflammation of the adipose tissue (AT) that
might develop into systemic inflammation, insulin resistance (IR) and an increased risk of …