The aim of this study was to analyze Toll‐like receptor (TLR) expression in preadipocytes
and mature adipocytes and to investigate whether TLR ligands influence the release of …

When humans eat more and exercise less, they tend to become obese and unhealthy. The
molecular pathways that link obesity to serious diseases like Type 2 diabetes and …

The anorexia of infection is part of the host's acute phase response (APR). Despite being
beneficial in the beginning, long lasting anorexia delays recovery and is ultimately …

The adipocyte-derived hormone leptin is an important regulator of appetite and energy
expenditure and is now appreciated for its ability to control innate and adaptive immune …

Although decreased T-cell function has been observed in obese human subjects and
genetically obese animals, the precise role of immune functions in obesity is still unclear. To …

Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …

The steadily increasing obesity epidemic affects currently 30% of western populations and is
causative for numerous disorders. It has been demonstrated that immune cells such as …

Although white AT can contribute to anti-infectious immune responses, it can also be
targeted and perturbed by pathogens. The AT's immune involvement is primarily due to …

Obesity is a major public health problem in the United States and worldwide. Further, obesity
is causally linked to the pathogenesis of insulin resistance, metabolic syndrome and type-2 …

The increase in the prevalence of obesity represents a worldwide phenomenon which is
associated with several chronic diseases. In this review, we summarize published data …