Liposomal vaccine delivery systems

M Henriksen-Lacey, KS Korsholm… - Expert opinion on …, 2011 - Taylor & Francis
Introduction: Liposomes remain at the forefront of drug and vaccine design owing to their
well-documented abilities to act as delivery vehicles. Nevertheless, the concept of liposomes …

Designing liposomal adjuvants for the next generation of vaccines

Y Perrie, F Crofts, A Devitt, HR Griffiths… - Advanced drug delivery …, 2016 - Elsevier
Liposomes not only offer the ability to enhance drug delivery, but can effectively act as
vaccine delivery systems and adjuvants. Their flexibility in size, charge, bilayer rigidity and …

Liposomes used as a vaccine adjuvant-delivery system: From basics to clinical immunization

N Wang, M Chen, T Wang - Journal of Controlled Release, 2019 - Elsevier
Liposomes are widely utilized as a carrier to improve therapeutic efficacy of agents thanks to
their merits of high loading capacity, targeting delivery, reliable protection of agents, good …

Liposome-based delivery system for vaccine candidates: constructing an effective formulation

AK Giddam, M Zaman, M Skwarczynski, I Toth - Nanomedicine, 2012 - Taylor & Francis
The discovery of liposomes in 1965 by Bangham and coworkers changed the prospects of
drug delivery systems. Since then, the application of liposomes as vaccine delivery systems …

A case-study investigating the physicochemical characteristics that dictate the function of a liposomal adjuvant

Y Perrie, E Kastner, R Kaur, A Wilkinson… - Human vaccines & …, 2013 - Taylor & Francis
A range of particulate delivery systems have been considered as vaccine adjuvants. Of
these systems, liposomes offer a range of advantages including versatility and flexibility in …

Design considerations for liposomal vaccines: influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens

DS Watson, AN Endsley, L Huang - Vaccine, 2012 - Elsevier
Liposomes (phospholipid bilayer vesicles) are versatile and robust delivery systems for
induction of antibody and T lymphocyte responses to associated subunit antigens. In the last …

Cationic liposomes as vaccine adjuvants

D Christensen, KS Korsholm, I Rosenkrands… - Expert review of …, 2007 - Taylor & Francis
Cationic liposomes are lipid-bilayer vesicles with a positive surface charge that have re-
emerged as a promising new adjuvant technology. Although there is some evidence that …

Cationic liposomes as vaccine adjuvants

D Christensen, KS Korsholm, P Andersen… - Expert review of …, 2011 - Taylor & Francis
The application of cationic liposomes as vaccine delivery systems and adjuvants has been
investigated extensively over the last few decades. However, cationic liposomes are, in …

Vaccine adjuvant systems: enhancing the efficacy of sub-unit protein antigens

Y Perrie, AR Mohammed, DJ Kirby, SE McNeil… - International journal of …, 2008 - Elsevier
Vaccination remains a key tool in the protection and eradication of diseases. However, the
development of new safe and effective vaccines is not easy. Various live organism based …

Liposomal adjuvants for human vaccines

CR Alving, Z Beck, GR Matyas… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Liposomes are well-known as drug carriers, and are now critical components of
two of six types of adjuvants present in licensed vaccines. The liposomal vaccine adjuvant …