The recently identified histamine H 4 receptor has revealed a potential new complexity for
the role of histamine in the immune system. To begin to understand the role of this receptor …

The histamine H4 receptor (H4R) is involved in the chemotaxis of leukocytes and mast cells
to sites of inflammation and is suggested to be a potential drug target for asthma and allergy …

The elucidation of the human genome has had a major impact on histamine receptor
research. The identification of the human H4 receptor by several groups has been …

Starting from the sequence of the human histamine H3 receptor (hH3R) cDNA, we have
cloned the corresponding rat cDNA. Whereas the two deduced proteins show 93.5% overall …

Various histamine derivatives were investigated at the human H3 receptor (H3R) and H4
receptor (H4R) stably expressed in human embryonic kidney (HEK)‐293 cells using [125I] …

Human and rat histamine H3 receptors were recombinantly expressed and characterized
using receptor binding and a functional cAMP assay. Seven of nine agonists had similar …

The histamine H 3 receptor was discovered 15 years ago, and many potent and selective H
3 receptor agonists and antagonists have since been developed. Currently, much attention …

The recent cloning and characterization of the human histamine H3 receptor cDNA marked
a significant step toward a greater understanding of the role of this receptor in the central …

Human, guinea pig and rat histamine H3 receptors have been investigated at both
pharmacological and molecular levels in recent years. Here we report the cloning …

We tested several histamine H1 receptor (H1R) and antagonists for their differences in
agonists binding affinities between human and guinea pig H1Rs transiently expressed in …