National Kidney Foundation CKD staging has allowed uniformity in studies on CKD.
However, early diagnosis and predicting progression to end stage renal disease are yet to …

The analysis of serum endogenous peptides holds promise for disease study and drug
discovery, whereas it is relatively unexplored given its challenges in analysis reproducibility …

Chronic kidney disease (CKD) is a significant public health problem, and progression to end‐
stage renal disease leads to dramatic increases in morbidity and mortality. The mechanisms …

Background An improvement in the glomerular filtration rate (GFR) of chronic kidney disease
patients has been an underestimated clinical outcome. Although this may be considered as …

Background With the help of proteomics technology, the human plasma and urine
proteomes, which closely represent the protein compositions of the input and output of the …

Peptidomics techniques have allowed the identification of thousands of peptides that are
derived from proteins in body fluids, despite the considerable challenges behind sample …

Introduction: Inter-individual variability in response to drug treatment has induced an
increased demand for decisions via personalize medicine. Also, the contribution of …

Glomerulopathies with nephrotic syndrome that are resistant to therapy often progress to
end-stage chronic kidney disease (CKD) and require timely and accurate diagnosis …

Introduction Human urine is a complex matrix of proteins, endogenous peptides, lipids, and
metabolites. The level of any or all of these components can reflect the pathophysiological …

Non-invasive urinary peptide biomarkers are able to detect and predict chronic kidney
disease (CKD). Moreover, specific urinary peptides enable discrimination of different CKD …