Comprehensive assessment of the long‐term safety of pirfenidone in patients with idiopathic pulmonary fibrosis

D Valeyre, C Albera, WZ Bradford, U Costabel… - …, 2014 - Wiley Online Library
Background and objective Pirfenidone is an oral antifibrotic agent that is approved in several
countries for the treatment of idiopathic pulmonary fibrosis (IPF). We performed a …

[HTML][HTML] Efficacy of pirfenidone for idiopathic pulmonary fibrosis: an Italian real life study

S Harari, A Caminati, C Albera, C Vancheri, V Poletti… - Respiratory …, 2015 - Elsevier
Summary Background In this retrospective Italian study, which involved all major national
interstitial lung diseases centers, we evaluated the effect of pirfenidone on disease …

Open-label compassionate use one year-treatment with pirfenidone to patients with chronic pulmonary fibrosis

S Nagai, K Hamada, M Shigematsu, M Taniyama… - Internal …, 2002 - jstage.jst.go.jp
Objective We attempted to evaluate the feasibility (therapeutic efficacy, tolerance, and
clinical courses after treatment) of pirfenidone, an anti-fibrotic drug for patients with chronic …

Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo …

J Behr, A Prasse, M Kreuter, J Johow… - The Lancet …, 2021 - thelancet.com
Background Pirfenidone has been shown to slow disease progression in patients with
idiopathic pulmonary fibrosis (IPF). However, there are few treatment options for progressive …

Pirfenidone in idiopathic pulmonary fibrosis

H Taniguchi, M Ebina, Y Kondoh… - European …, 2010 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease without proven effective
therapy. A multicentre, double-blind, placebo-controlled, randomised phase III clinical trial …

Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with …

SD Nathan, C Albera, WZ Bradford, U Costabel… - Thorax, 2016 - thorax.bmj.com
Background The assessment of treatment response in idiopathic pulmonary fibrosis (IPF) is
complicated by the variable clinical course. We examined the variability in the rate of …

Efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis with more preserved lung function

C Albera, U Costabel, EA Fagan… - European …, 2016 - Eur Respiratory Soc
This post hoc analysis examined the differences in idiopathic pulmonary fibrosis disease
progression and the effects of pirfenidone in patients stratified by more preserved versus …

Efficacy and safety of pirfenidone for idiopathic pulmonary fibrosis

Y Takeda, K Tsujino, T Kijima… - Patient preference and …, 2014 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a devastating chronic fibrotic lung disease. Although
the precise cause of the disease is still unknown, recent studies have shown that the …

Analysis of lung function and survival in RECAP: An open-label extension study of pirfenidone in patients with idiopathic pulmonary fibrosis.

U Costabel, C Albera, WZ Bradford… - … Vasculitis, and Diffuse …, 2014 - europepmc.org
Background RECAP is an open-label extension study evaluating pirfenidone in patients with
idiopathic pulmonary fibrosis (IPF) who completed the Phase 3 CAPACITY program …

Pirfenidone in progressive pulmonary fibrosis: a systematic review and meta-analysis

M Ghazipura, MJ Mammen, BD Bissell… - Annals of the …, 2022 - atsjournals.org
Background: The American Thoracic Society, European Respiratory Society, Japanese
Respiratory Society, and Asociación Latinoamericana del Tórax convened to update clinical …