[HTML][HTML] Saponins from Sanguisorba officinalis improve hematopoiesis by promoting survival through FAK and Erk1/2 activation and modulating cytokine production in …

X Chen, B Li, Y Gao, J Ji, Z Wu, S Chen - Frontiers in Pharmacology, 2017 - frontiersin.org
Radix Sanguisorbae, the root of Sanguisorba officinalis L. is used as traditional Chinese
medicine. In recent decades, it has been reported to be clinically effective against …

[HTML][HTML] Saponins From Paris forrestii (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway

Q Lu, Y He, Y Wang, L Gao, Y Zheng… - Frontiers in …, 2018 - frontiersin.org
Saponins are amphipathic glycosides found in traditional Chinese medicines. In the present
study, we isolated a panel of saponins from Paris forrestii (Takht.) H. Li, a unique plant found …

Protective effects of tannins in Sanguisorbae Radix on myelosuppression mice

Y Xiong, Q Yu, J Zou, Y He, S Zhang, R Xu… - Chinese Herbal …, 2014 - Elsevier
Objective To explore the protective effects of tannins in Sanguisorba Radix (TSR) on
myelosuppression mice induced by cyclophosphamide (CTX). Methods TSR was ig given at …

[HTML][HTML] Five Active Components Compatibility of Astragali Radix and Angelicae Sinensis Radix Protect Hematopoietic Function Against Cyclophosphamide-Induced …

W Zhang, J Zhu, H Xu, XP Huang, XD Liu… - Frontiers in …, 2019 - ncbi.nlm.nih.gov
Although the compatibility of Astragali Radix (AR) and Angelicae Sinensis Radix (ASR) has
favorable effect on promoting hematopoiesis in traditional Chinese medicine (TCM), the …

Mechanisms by which Astragalus membranaceus injection regulates hematopoiesis in myelosuppressed mice

XL Zhu, BD Zhu - Phytotherapy Research: An International …, 2007 - Wiley Online Library
The aim of this study was to investigate the mechanism underlying the effects of Astragalus
membranaceus injection (AMI) on myelopoiesis in myelosuppressed mice. At 72 h after …

Establishment of an in vitro system based on AGM-S3 co-culture for screening traditional herbal medicines that stimulate hematopoiesis

J Chang, W Sun, J Zeng, Y Xue, Y Zhang, X Pan… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Spatholobus suberectus Dunn is a traditional
Chinese medicine (TCM) that can activate blood, dispel stasis, inhibit platelet aggregation …

Systems pharmacology reveals the mechanism of Astragaloside IV in improving immune activity on cyclophosphamide-induced immunosuppressed mice

J Yao, J Liu, Y He, L Liu, Z Xu, X Lin, N Liu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Myelosuppression, also known as bone marrow
suppression (BMS), is a pathological phenomenon of the decrease in the production of …

[HTML][HTML] Astragaloside IV and Saponins of Rhizoma Polygonati Cure Cyclophosphamide-Induced Myelosuppression in Lung Adenocarcinoma via Down-Regulating …

X Gu, L Zhu, Z Xu, K Shen - Frontiers in Oncology, 2021 - frontiersin.org
Our previous study revealed that Shuanghuang Shengbai granule could cure the
myelosuppression induced by cyclophosphamide (CTX) in lung cancer. However, its …

[HTML][HTML] Astragalus polysaccharide has a protective effect on hematopoiesis in an irradiated mouse model and decreases apoptosis in megakaryocytes

L Li, W Xu, C Yi, Y Cheng, H Xin… - Molecular …, 2021 - spandidos-publications.com
Huangqi, the dried root of Radix Astragali, is an essential herb in Traditional Chinese
Medicine and has been used to promote hematopoiesis for centuries. Astragalus …

[HTML][HTML] Ginseng-derived panaxadiol saponins promote hematopoiesis recovery in cyclophosphamide-induced myelosuppressive mice: potential novel treatment of …

X Sun, Y Zhao, S Qian, R Gao, L Yin, L Wang… - Chinese journal of …, 2018 - Springer
Objective To investigate the potential efficacy of panaxadiol saponins component (PDS-C), a
biologically active fraction isolated from total ginsenosides, to reverse chemotherapy …