Intra-tumoral immune cells promote the stemness of cancer stem cells (CSCs) in the tumor
microenvironment (TME). CSCs promote tumor progression, relapse, and resistance to …

Tumour-associated macrophages are an essential component of the tumour
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …

Tumor-associated macrophages (TAMs) are key contributors to antitumor immunity. Here,
we present a protocol to drive human monocyte-macrophage differentiation using tumor …

As fundamental immune cells in innate and adaptive immunity, macrophages engage in a
double-edged relationship with cancer. Dissecting the character of macrophages in cancer …

Tumor-associated macrophages are regarded as tumor-enhancers as they have key roles in
the subversion of adaptive immunity and in inflammatory circuits that promote tumor …

Tumor-associated macrophages (TAMs) are a major component of the tumor immune
microenvironment (TIME) and are associated with a poor prognostic factor in several …

Chimeric antigen receptor (CAR)-expressing macrophages (CAR-M) have a great potential
to improve cancer therapy, as shown from several recent preclinical studies. However …

Monocytes in peripheral blood circulation are the precursor of essential cells that control
tumor progression, that include tumor-associated macrophages (TAMs), dendritic cells …

In the quest for better medicines, attention is increasingly turning to cell-based therapies.
The rationale is that infused cells can provide a targeted therapy to precisely correct a …

Adoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made
tremendous progress with five CAR T therapies approved by the US Food and Drug …