Non-esterified fatty acids (NEFA) are the primary energy fuel for most tissues under fasting
conditions. Their release into the circulation results partly from the hydrolysis of …

Insulin inhibits systemic nonesterified fatty acid (NEFA) flux to a greater degree than glucose
or any other metabolite. This remarkable effect is mainly due to insulin-mediated inhibition of …

There is a widespread acceptance in the literature that plasma nonesterified fatty acids
(NEFA), also called free fatty acids (FFA), can mediate many adverse metabolic effects, most …

Disturbances in pathways of lipolysis and fatty acid handling are of importance in the
aetiology of obesity and type 2 diabetes mellitus. There is evidence that a lowered …

In adipose, insulin functions to suppress intracellular lipolysis and secretion of nonesterified
fatty acid (NEFA) into plasma. We applied glucose and NEFA minimal models (MM) …

Elevation of plasma nonesterified fatty acid (NEFA) levels has been shown to impair the
actions of insulin on peripheral glucose uptake and suppression of hepatic glucose output …

Insulin increases plasma nonesterified fatty acid (NEFA) clearance in humans, but whether
this is independent of change in plasma NEFA appearance is currently unknown. Nine …

Plasma nonesterified fatty acid (NEFA) levels are increased in the insulin-stimulated state in
non-insulin-dependent diabetes mellitus (NIDDM) and may contribute to the decrease in …

Non-insulin-dependent diabetes (NIDDM) is characterized by overproduction of glucose,
decreased effects of insulin on glucose utilization and production, and a defect in glucose …

It has long been recognized that acute elevation of non-esterified fatty acids (NEFA)
stimulates insulin secretion to a moderate extent both in vitro and in vivo. The effects of …