Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity

F Borges, F Roleira, N Milhazes… - Current medicinal …, 2005 - ingentaconnect.com
Coumarins, also known as benzopyrones, are present in remarkable amounts in plants,
although their presence has also been detected in microorganisms and animal sources. The …

Simple coumarins: privileged scaffolds in medicinal chemistry

MFM Borges, FMF Roleira, N Milhazes… - Frontiers in …, 2010 - books.google.com
Coumarins, also known as benzopyrones, are present in remarkable amounts in plants,
although their presence has also been detected in microorganisms and animal sources. The …

Coumarin compounds in medicinal chemistry: some important examples from the last years

TM Pereira, DP Franco, F Vitorio… - Current topics in …, 2018 - ingentaconnect.com
Coumarins are natural products characterized as 1, 2 benzopyrones widely distributed in
plants, as well as, in many species of fungi and bacteria. Nowadays, many synthetic …

Coumarin derivatives: an updated patent review (2015-2016)

A Detsi, C Kontogiorgis… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Coumarins belong to the benzopyrone family. They are naturally plant-derived
or synthetically obtained substances, presenting a wide variety of biological activities …

Progress in the chemistry of naturally occurring coumarins

SD Sarker, L Nahar - Progress in the Chemistry of Organic Natural …, 2017 - Springer
Coumarins are the largest group of 1-benzopyran derivatives found in plants. The initial
member of this group of compounds, coumarin (2 H-1-benzopyran-2-one), a fragrant …

Coumarin derivatives: an updated patent review (2012–2014)

AM Katsori, D Hadjipavlou-Litina - Expert opinion on therapeutic …, 2014 - Taylor & Francis
Introduction: Coumarins belong to the benzopyrones family. They are naturally plant-derived
and synthetically taken polyphenolic substances, presenting a wide variety of biological …

Coumarins—an important class of phytochemicals

MJ Matos, L Santana, E Uriarte, OA Abreu… - … and role in human …, 2015 - books.google.com
Phytochemicals are chemical compounds that occur naturally in the plant kingdom. Some
are responsible for the organoleptic properties of the natural sources in which they are …

A review on pharmacological properties of coumarins

D Srikrishna, C Godugu… - Mini reviews in medicinal …, 2018 - ingentaconnect.com
The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in many natural
products, displays diverse pharmacological properties. It has attracted the attention of …

Coumarin-based drugs: a patent review (2008–present)

C Kontogiorgis, A Detsi… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Coumarins are a group of plant-derived polyphenolic compounds. They belong
to the benzopyrones family and possess a wide variety of cytoprotective and modulatory …

Coumarins: old compounds with novel promising therapeutic perspectives

ME Riveiro, N De Kimpe, A Moglioni… - Current medicinal …, 2010 - ingentaconnect.com
Natural as well as synthetic coumarins have recently drawn much attention due to its broad
pharmacological activities. Many coumarins and their derivatives exert anti-coagulant, anti …