PURPOSE: To provide an overview of the current clinical management of retinoblastoma by
discussing the trends in the categorization, treatment, and recent advances in molecular …

Retinoblastoma can present in 1 or both eyes and is the most common intraocular
malignancy in childhood. It is typically initiated by biallelic mutation of the RB1 tumor …

Background Retinoblastoma is the most common primary intraocular malignancy in children.
The management of retinoblastoma is complex and depends on several factors. Methods …

Treatment of retinoblastoma has undergone significant advancements over the past few
decades, as globe-salvaging therapies with chemoreduction and focal consolidation are …

Retinoblastoma is the most common primary intraocular cancer in children. Representing
6.1% of all childhood cancer under the age of 5 years, 1 retinoblastoma primarily affects …

Retinoblastoma represents approximately 4% of all pediatric malignancies and is the most
common primary intraocular cancer in children. 1, 2 Worldwide, it is estimated that there are …

Background Retinoblastoma is a highly malignant tumor of the eye that manifests most often
in the first 3 years of life. Methods Published articles were reviewed to evaluate the clinical …

Retinoblastoma is the commonest primary ocular malignancy of childhood. There are two
forms—heritable and non heritable. Heritable retinoblastoma is a cancer susceptibility …

Progressive advances in the understanding of retinoblastoma pathogenesis continue to lead
treatment strategies. Improvements in the diagnosis and management of retinoblastoma are …

With an average incidence of 1 in every 18,000 live births, retinoblastoma is a rare type of
intraocular tumour found to affect patients during their early childhood. It is curable if …