Summary Using [3 H] 8-cyclopentyl-1, 3-dipropylxanthine (DPCPX), a 3 H-labeled A 1-
selective adenosine antagonist with high affinity and extremely low non-specific binding, it …

The effects of guanine nucleotides on binding of 8‐cyclopentyl‐1, 3‐[3H] dipropylxanthine
([3H] DPCPX), a highly selective A1 adenosine receptor antagonist, have been investigated …

Guamne nucleotides, divalent cations, and sodium differentially regulate agonist and
antagonist binding to adenosine A, receptors in brain membranes. Guanine nucleotides …

The effect of increasing doses of GTP on agonist and antagonist binding to adenosine A1-
receptors in different regions of rat brain was studied by autoradiography. A high …

A1 adenosine receptors were labeled in rat brain sections with the antagonist [3H] 8‐
cyclopentyl‐1, 3‐dipropylxanthine ([3H] DPCPX) and visualized at the light microscopic level …

The bovine brain A1-adenosine receptor was purified 8000-fold by affinity chromatography
on xanthine-amine-congener (XAC)-Sepharose. Addition of a 120-fold molar excess of a …

Cyclopentyl-1, 3-dipropylxanthine (PD 116,948) is a very potent, very A 1-selective
adenosine antagonist, with a K i of 0.46 nM in 3 H-CHA binding to A 1 receptors in rat whole …

1 Radioligand binding properties of the adenosine receptor ligands,[3H]‐1, 3‐dipropyl‐8‐
cyclopentylxanthine ([3H]‐DPCPX), and [3H]‐R‐phenylisopropyladenosine ([3H]‐R‐PIA) …

Signal transduction by A1 adenosine receptors was investigated by measuring the
modulation by adenosine agonists of guanosine-5'-O-(3-[35S] thio) triphosphate ([35S] GTP …

A series of 28 adenosine analogs and 17 xanthines has been assessed as inhibitors of
binding of N 6‐R‐[3H]‐phenylisopropyladenosine binding to A1 adenosine receptors in …