Re-evaluating the significance of estrone as an environmental estrogen

GT Ankley, D Feifarek, B Blackwell… - … science & technology, 2017 - ACS Publications
Studies worldwide have demonstrated the occurrence of feminized male fish at sites
impacted by human and animal wastes. A variety of chemicals could contribute to this …

Comparing biological effects and potencies of estrone and 17β-estradiol in mature fathead minnows, Pimephales promelas

AA Dammann, NW Shappell, SE Bartell… - Aquatic Toxicology, 2011 - Elsevier
The presence of endocrine active compounds such as estrogens in treated wastewater
effluent and their effects on aquatic life are causing concern among aquatic resource …

Fish multigeneration test with preliminary short‐term reproduction assay for estrone using Japanese medaka (Oryzias latipes)

A Nakamura, I Tamura, H Takanobu… - Journal of Applied …, 2015 - Wiley Online Library
The most potent chemicals potentially causing adverse effects on fish species are estrogens
in human waste. Sewage is a source of these estrogens and it is difficult to reduce. In …

Collapse of a fish population after exposure to a synthetic estrogen

KA Kidd, PJ Blanchfield, KH Mills… - Proceedings of the …, 2007 - National Acad Sciences
Municipal wastewaters are a complex mixture containing estrogens and estrogen mimics
that are known to affect the reproductive health of wild fishes. Male fishes downstream of …

Elevation of serum 17-β-estradiol in channel catfish following injection of 17-β-estradiol, ethynyl estradiol, estrone, estriol and estradiol-17-β-glucuronide

F Tilton, WH Benson, D Schlenk - Environmental Toxicology and …, 2001 - Elsevier
17-β-Estradiol is naturally converted in numerous organisms to various derivatives/
metabolites, which may be excreted from the organism into its immediate external …

Ethinyloestradiol—an undesired fish contraceptive?

DGJ Larsson, M Adolfsson-Erici, J Parkkonen… - Aquatic toxicology, 1999 - Elsevier
Environmental oestrogens are natural or synthetic substances present in the environment,
which imitate the effects of endogenous oestrogen. Oestrogenic substances were identified …

Short‐term exposure to 17α‐ethynylestradiol decreases the fertility of sexually maturing male rainbow trout (Oncorhynchus mykiss)

IR Schultz, A Skillman, JM Nicolas… - … and Chemistry: An …, 2003 - Wiley Online Library
The synthetic estrogen 17α‐ethynylestradiol (EE2) is a commonly used oral contraceptive
that has been increasingly detected in sewage effluents. This study determined whether EE2 …

Adverse reproductive effects in male fathead minnows (Pimephales promelas) exposed to environmentally relevant concentrations of the natural oestrogens …

GH Panter, RS Thompson, JP Sumpter - Aquatic Toxicology, 1998 - Elsevier
Recent research has shown that low concentrations of natural and synthetic oestrogens are
present in sewage treatment works effluents. However, the effects of these oestrogens on …

Effects of waterborne exposure of 17 β-estradiol on secondary sex characteristics and gonads of fathead minnows (Pimephales promelas)

SR Miles-Richardson, VJ Kramer, SD Fitzgerald… - Aquatic Toxicology, 1999 - Elsevier
Environmental contaminants with estrogenic activity have recently received attention
because of their potential effects on the reproductive efficiency of humans and wildlife. This …

Estrogenic potency of chemicals detected in sewage treatment plant effluents as determined by in vivo assays with Japanese medaka (Oryzias latipes)

CD Metcalfe, TL Metcalfe, Y Kiparissis… - … and Chemistry: An …, 2001 - Wiley Online Library
Gonadal intersex and high prevalences of the female phenotype have been observed in fish
populations in urbanized areas. Environmental estrogens discharged in sewage treatment …