Bioprocessing strategies to improve heterologous protein production in filamentous fungal fermentations
L Wang, D Ridgway, T Gu, M Moo-Young - Biotechnology advances, 2005 - Elsevier
Filamentous fungi have long been used for the production of metabolites and enzymes. With
developments in genetic engineering and molecular biology, filamentous fungi have also …
developments in genetic engineering and molecular biology, filamentous fungi have also …
Increased Heterologous Protein Production in Aspergillusniger Fermentation through Extracellular Proteases Inhibition by Pelleted Growth
The dependence of filamentous fungal protease secretion on morphology was investigated
by employing the recombinant Aspergillus niger strain AB4. 1 [pgpdAGLAGFP] which …
by employing the recombinant Aspergillus niger strain AB4. 1 [pgpdAGLAGFP] which …
[HTML][HTML] Heterologous protein production in filamentous fungi
D Liu, S Garrigues, RP de Vries - Applied microbiology and biotechnology, 2023 - Springer
Filamentous fungi are able to produce a wide range of valuable proteins and enzymes for
many industrial applications. Recent advances in fungal genomics and experimental …
many industrial applications. Recent advances in fungal genomics and experimental …
Approaches for refining heterologous protein production in filamentous fungi
R Sharma, M Katoch, PS Srivastava… - World Journal of …, 2009 - Springer
Fungi combine the advantages of a microbial system such as a simple fermentability with the
capability of secreting proteins that are modified according to a general eukaryotic scheme …
capability of secreting proteins that are modified according to a general eukaryotic scheme …
Heterologous gene expression in filamentous fungi
X Su, G Schmitz, M Zhang, RI Mackie… - Advances in applied …, 2012 - Elsevier
Filamentous fungi are critical to production of many commercial enzymes and organic
compounds. Fungal-based systems have several advantages over bacterial-based systems …
compounds. Fungal-based systems have several advantages over bacterial-based systems …
Production of recombinant proteins by filamentous fungi
OP Ward - Biotechnology advances, 2012 - Elsevier
The initial focus of recombinant protein production by filamentous fungi related to exploiting
the extraordinary extracellular enzyme synthesis and secretion machinery of industrial …
the extraordinary extracellular enzyme synthesis and secretion machinery of industrial …
[HTML][HTML] Fungal cell factories for efficient and sustainable production of proteins and peptides
M Lübeck, PS Lübeck - Microorganisms, 2022 - mdpi.com
Filamentous fungi are a large and diverse taxonomically group of microorganisms found in
all habitats worldwide. They grow as a network of cells called hyphae. Since filamentous …
all habitats worldwide. They grow as a network of cells called hyphae. Since filamentous …
Strategies for improving heterologous protein production from filamentous fungi
DB Archer, DJ Jeenes, DA Mackenzie - Antonie Van Leeuwenhoek, 1994 - Springer
Despite the naturally high capacity for protein secretion by many species of filamentous
fungi, secteted yields of many heterologous proteins have been comparatively low. The …
fungi, secteted yields of many heterologous proteins have been comparatively low. The …
Heterologous protein expression in filamentous fungi
KMH Nevalainen, VSJ Te'o, PL Bergquist - Trends in biotechnology, 2005 - cell.com
Filamentous fungi are commonly used in the fermentation industry for the large-scale
production of proteins–mainly industrial enzymes. Recent advances in fungal genomics and …
production of proteins–mainly industrial enzymes. Recent advances in fungal genomics and …
Disruption of ten protease genes in the filamentous fungus Aspergillus oryzae highly improves production of heterologous proteins
J Yoon, J Maruyama, K Kitamoto - Applied microbiology and biotechnology, 2011 - Springer
Proteolytic degradation by secreted proteases into the culture medium is one of the
significant problems to be solved in heterologous protein production by filamentous fungi …
significant problems to be solved in heterologous protein production by filamentous fungi …
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