To identify and characterize those proteins involved in taste transduction, we cloned G
proteins and phosphodiesterases from rat taste tissue. Using degenerate primers …

The taste-specific G-protein alpha-subunit, alpha-gustducin, was expressed using a
baculovirus based system. alpha-Gustducin was demonstrated to be myristoylated and was …

In the vertebrate taste cell, heterotrimeric guanine nucleotide‐binding proteins (G proteins)
are involved in the transduction of both bitter and sweet taste stimulants. The bitter …

The recent application of molecular biological techniques to taste cells has led to the
identification and cloning of a number of proteins that are involved in signal transduction …

The transduction of responses to bitter and sweet compounds utilizes guanine nucleotide
binding proteins (G proteins) and their coupled receptors. α-Gustducin, a transducin-like G …

Many bitter stimuli are believed to bind to specific G-protein-coupled membrane receptors
on taste cells. Despite the compelling evidence for its pivotal role in bitter taste sensation, a …

Gustducin is a transducin-like G protein selectively expressed in taste receptor cells. The α
subunit of gustducin (α-gustducin) is critical for transduction of responses to bitter or sweet …

The G-protein subunit α-gustducin, which is similar to rod transducin, has been implicated in
the transduction of both sweet-and bitter-tasting substances. In rodents, there are differences …

Taste cells respond to a wide variety of chemical stimuli: certain ions are perceived as salty
(Na+) or sour (H+); other small molecules are perceived as sweet (sugars) and bitter …

Expression of the α-subunit of the taste-specific G protein α-gustducin and the glycolytic
enzyme neuron-specific enolase (NSE) was investigated immunohistochemically in human …