Growth Phase-Dependent Regulation of the Extracytoplasmic Stress Factor, σE, by Guanosine 3′,5′-Bispyrophosphate (ppGpp)

A Costanzo, SE Ades - Journal of bacteriology, 2006 - Am Soc Microbiol
The sigma subunit of procaryotic RNA polymerases is responsible for specific promoter
recognition and transcription initiation. In addition to the major sigma factor, σ70, in …

Interplay of global regulators and cell physiology in the general stress response of Escherichia coli

R Hengge-Aronis - Current opinion in microbiology, 1999 - Elsevier
Under various stress conditions, two sigma subunits of RNA polymerase, σs and σ70,
coexist in Escherichia coli cells. In contrast to σ70, σs is subject to intricate regulation and …

[HTML][HTML] Trouble is coming: Signaling pathways that regulate general stress responses in bacteria

S Gottesman - Journal of Biological Chemistry, 2019 - ASBMB
Bacteria can rapidly and reversibly respond to changing environments via complex
transcriptional and post-transcriptional regulatory mechanisms. Many of these adaptations …

Molecular analysis of the regulation of csiD, a carbon starvation-inducible gene in Escherichia coli that is exclusively dependent on σS and requires activation by …

C Marschall, V Labrousse, M Kreimer… - Journal of molecular …, 1998 - Elsevier
The general stress-induced sigma subunit σS of Escherichia coli RNA polymerase is closely
related to the vegetative sigma factor σ70. In view of their very similar promoter specificity in …

[HTML][HTML] General pathway for turning on promoters transcribed by RNA polymerases containing alternative σ factors

RL Gourse, W Ross, ST Rutherford - Journal of Bacteriology, 2006 - Am Soc Microbiol
Signal coordinating a response by multiple RNAP holoenzymes. In Escherichia coli, the vast
majority of transcription results from the RNA polymerase (RNAP) holoenzyme containing …

Co‐ordinated regulation of the extracytoplasmic stress factor, sigmaE, with other Escherichia coli sigma factors by (p)ppGpp and DksA may be achieved by specific …

S Gopalkrishnan, H Nicoloff, SE Ades - Molecular microbiology, 2014 - Wiley Online Library
The E. coli alternative sigma factor, σE, transcribes genes required to maintain the cell
envelope and is activated by conditions that destabilize the envelope. σE is also activated …

The extracytoplasmic function (ECF) sigma factors

JD Helmann - 2002 - Elsevier
Bacterial sigma (σ) factors are an essential component of RNA polymerase and determine
promoter selectivity. The substitution of one σ factor for another can redirect some or all of …

The cellular concentration of the sigma S subunit of RNA polymerase in Escherichia coli is controlled at the levels of transcription, translation, and protein stability.

R Lange, R Hengge-Aronis - Genes & development, 1994 - genesdev.cshlp.org
The second vegetative sigma factor sigma S (encoded by the rpoS gene) is the master
regulator in a complex regulatory network that governs the expression of many stationary …

The σS subunit of RNA polymerase as a signal integrator and network master regulator in the general stress response in Escherichia coli

E Klauck, A Typas, R Hengge - Science progress, 2007 - journals.sagepub.com
The σS (RpoS) subunit of RNA polymerase in Escherichia coli is a key master regulator
which allows this bacterial model organism and important pathogen to adapt to and survive …

ppGpp and DksA likely regulate the activity of the extracytoplasmic stress factor σE in Escherichia coli by both direct and indirect mechanisms

A Costanzo, H Nicoloff, SE Barchinger… - Molecular …, 2008 - Wiley Online Library
One of the major signalling pathways responsible for intercompartmental communication
between the cell envelope and cytoplasm in Escherichia coli is mediated by the alternative …