We report a severe hemorrhagic disorder in two pediatric patients with lupus anticoagulant
(LA) associated to acquired factor II (prothrombin) deficiency. In both patients, hemorrhagic …

A 17-year-old girl was admitted to our department with a hemorrhagic syndrome due to a
serious coagulopathy; prothrombin time (PT) INR was 2.46 and the activated partial …

Purpose: We present the association of a lupus anticoagulant with hypoprothrombinemia in
a 5-year-old girl, who presented with ecchymoses and a hematoma. This coagulopathy …

Lupus anticoagulants (LA) are part of a large group of autoanti-bodies thought to be directed
against at least two phospholipid-binding plasma proteins, pz-glycoprotein I and …

Discussion Since its first description by Rapaport in 1960 [1], the lupus anticoagulant-
hypoprothrombinemia syndrome (HLAS) has been well documented. It is a rare event: at the …

Lupus anticoagulant, also known as lupus antibody, is generally associated with thrombosis
rather than bleeding events. Lupus anticoagulant-hypoprothrombinemia syndrome in …

Lupus anticoagulant hypoprothrombinemia syndrome (LAHPS) is a rare disorder
characterized by a bleeding tendency due to factor II deficiency associated with the …

Patients with lupus anticoagulant (LA), a thrombotic risk factor, along with decreased
prothrombin (FII) activity are classified as lupus anticoagulant-hypoprothrombinemia …

Three children with systemic lupus erythematosus who developed hemorrhagic tendencies
as a consequence of a clotting factor II (prothrombin) deficiency are described. All three …

Lupus anticoagulant is a misnomer as it is commonly associated with thromboembolic
events. In few cases, the name retains its literal meaning when it characterizes patients with …