[HTML][HTML] In vitro and in vivo evaluation of a small-caliber coaxial electrospun vascular graft loaded with heparin and VEGF

YT Hu, XD Pan, J Zheng, WG Ma, LZ Sun - International Journal of Surgery, 2017 - Elsevier
Introduction To date, clinically available expanded polytetrafluoro-ethylene (ePTFE)
vascular grafts are suboptimal for reconstructing small caliber (D< 6 mm) arteries, owing to …

Endothelialization of electrospun polycaprolactone (PCL) small caliber vascular grafts spun from different polymer blends

D Pfeiffer, C Stefanitsch, K Wankhammer… - … Research Part A, 2014 - Wiley Online Library
Small caliber vascular grafts represent a challenge to material scientists. In contrast to large
caliber grafts, prostheses with diameter< 6 mm, lead to increased hemodynamic …

Evaluation of electrostatically endothelial cell seeded expanded polytetrafluoroethylene grafts in a canine femoral artery model

C Fields, A Cassano, RG Makhoul… - Journal of …, 2002 - journals.sagepub.com
(1) Purpose: The purpose of this study was to evaluate the extent (luminal coverage) of the
endothelial cell (EC) lining/neointimal development and the thromboresistance of …

Heparin loading and pre-endothelialization in enhancing the patency rate of electrospun small-diameter vascular grafts in a canine model

C Huang, S Wang, L Qiu, Q Ke, W Zhai… - ACS applied materials & …, 2013 - ACS Publications
We herein proved that the two commonly used antithrombotic methods, heparin loading and
pre-endothelialization could both greatly enhance the patency rate of a small-diameter graft …

Physico-mechanical and biological evaluation of heparin/VEGF-loaded electrospun polycaprolactone/decellularized rat aorta extracellular matrix for small-diameter …

JP Cuenca, HJ Kang, MAA Fahad, M Park… - Journal of …, 2022 - Taylor & Francis
Although the continuous development of small-diameter vascular grafts (SDVGs)(D< 5 mm)
continues, most vascular grafts are made from synthetic polymers, which lead to serious …

Evaluation of human umbilical vein endothelial cells growth onto heparin-modified electrospun vascular grafts

PC Caracciolo, P Diaz-Rodriguez, I Ardao… - International Journal of …, 2021 - Elsevier
One of the main challenges of cardiovascular tissue engineering is the development of
bioresorbable and compliant small-diameter vascular grafts (SDVG) for patients where …

Improved healing of small-caliber, long-fibril expanded polytetrafluoroethylene vascular grafts by covalent bonding of fibronectin

T Shimada, T Nishibe, H Miura, K Hazama, H Kato… - Surgery today, 2004 - Springer
Purpose To evaluate the intermediate performance of small-caliber, long-fibril expanded
polytetrafluoroethylene (ePTFE) vascular grafts pretreated with covalent bonding of …

Electrospun compliant heparinized elastic vascular graft for improving the patency after implantation

S Qiu, J Du, T Zhu, H Zhang, S Chen, C Wang… - International Journal of …, 2023 - Elsevier
The low patency rate after artificial blood vessel replacement is mainly due to the ineffective
use of anticoagulant factors and the mismatch of mechanical compliance after …

Achieving better patency rates and neoendothelialization in 1‐millimeter polytetrafluoroethylene grafts by varying fibril length and wall thickness

M Lanzetta, E Owen - Microsurgery, 1992 - Wiley Online Library
This study evaluates the effects of different fibril lengths and wall thicknesses on patency
and neoendothelialization in 1 mm inner diameter polytetrafluoroethylene (PTFE; Gore‐Tex) …

Considerations in the development of small-diameter vascular graft as an alternative for bypass and reconstructive surgeries: a review

FO Obiweluozor, GA Emechebe, DW Kim… - Cardiovascular …, 2020 - Springer
Background Current design strategies for small diameter vascular grafts (< 6 mm internal
diameter; ID) are focused on mimicking native vascular tissue because the commercially …