Genetic variation in lean body mass, changes of appetite and weight loss in response to diet interventions: The POUNDS Lost trial

X Li, T Zhou, H Ma, Y Heianza… - Diabetes, Obesity …, 2020 - Wiley Online Library
Aim To investigate whether the genetic risk score (GRS) for lean body mass (LBM) modified
the effects of weight‐loss diets on changes in appetite and adiposity among overweight and …

[HTML][HTML] Disentangling the genetics of lean mass

D Karasik, MC Zillikens, YH Hsu, A Aghdassi… - The American journal of …, 2019 - Elsevier
Background Lean body mass (LM) plays an important role in mobility and metabolic
function. We previously identified five loci associated with LM adjusted for fat mass in …

Distinct genetic subtypes of adiposity and glycemic changes in response to weight-loss diet intervention: the POUNDS Lost trial

Y Chen, T Zhou, D Sun, X Li, H Ma, Z Liang… - European journal of …, 2021 - Springer
Purpose Obesity is a heterogeneous condition and distinct adiposity subtypes may
differentially affect type 2 diabetes risk. We assessed relations between genetically …

The Personalized Nutrition Study (POINTS): evaluation of a genetically informed weight loss approach, a Randomized Clinical Trial

C Höchsmann, S Yang, JM Ordovás, JL Dorling… - Nature …, 2023 - nature.com
Weight loss (WL) differences between isocaloric high-carbohydrate and high-fat diets are
generally small; however, individual WL varies within diet groups. Genotype patterns may …

Genetic variation of fasting glucose and changes in glycemia in response to 2-year weight-loss diet intervention: the POUNDS LOST trial

T Wang, T Huang, Y Zheng, J Rood, GA Bray… - International journal of …, 2016 - nature.com
Objective: Weight-loss intervention through diet modification has been widely used to
improve obesity-related hyperglycemia; however, little is known about whether genetic …

Genetic predictors of weight loss in overweight and obese subjects

I Lamiquiz-Moneo, R Mateo-Gallego, AM Bea… - Scientific reports, 2019 - nature.com
The aim of our study was to investigate a large cohort of overweight subjects consuming a
homogeneous diet to identify the genetic factors associated with weight loss that could be …

[HTML][HTML] Effect of low-fat vs low-carbohydrate diet on 12-month weight loss in overweight adults and the association with genotype pattern or insulin secretion: the …

CD Gardner, JF Trepanowski, LC Del Gobbo… - Jama, 2018 - jamanetwork.com
Importance Dietary modification remains key to successful weight loss. Yet, no one dietary
strategy is consistently superior to others for the general population. Previous research …

[HTML][HTML] Diet quality and genetic association with body mass index: results from 3 observational studies

M Ding, C Ellervik, T Huang, MK Jensen… - The American Journal of …, 2018 - Elsevier
Background It is unknown whether dietary quality modifies genetic association with body
mass index (BMI). Objective This study examined whether dietary quality modifies genetic …

[HTML][HTML] Dietary Mediators of the Genetic Susceptibility to Obesity—Results from the Quebec Family Study

R Jacob, C Bertrand, C Llewellyn, C Couture… - The Journal of …, 2022 - Elsevier
Background Recent studies showed that eating behaviors such as disinhibition, emotional
and external eating, and snacking mediate genetic susceptibility to obesity. It remains …

[HTML][HTML] Impact of dietary and obesity genetic risk scores on weight gain

L Baratali, M Mean, P Marques-Vidal - The American Journal of Clinical …, 2021 - Elsevier
Background Whether genetic background and/or dietary behaviors influence weight gain in
middle-aged subjects is debated. Objective To assess whether genetic background and/or …