Over the last decade, the emergence of several novel therapeutic approaches has changed
the therapeutic perspective of human malignancies. Adoptive immunotherapy through …

Cancer has recently been identified as the leading cause of mortality worldwide. Several
conventional treatments and cytotoxic immunotherapies have been developed and made …

For years, cancer treatment was dominated by chemotherapy, radiation therapy, and stem
cell transplantation. New insights into genetic characteristics of leukemic cells have initiated …

Progress in our understanding of basic immunology along with the advent of bioengineering
technologies have made possible the production of human T-cells expressing Chimeric …

Simple Summary Chimeric antigen receptor T cells (CAR T-cells) are engineered T cells that
target tumor-associated antigens. CAR T-cell therapy is a novel developed immunotherapy …

For many years, the methods of cancer treatment are usually surgery, chemotherapy and
radiation therapy. Although these methods help to improve the condition, most tumors still …

Chimeric antigen receptor T-cell (CAR-T) therapy is a revolutionary cancer treatment
modality where a patient's own T cells are collected and engineered ex vivo to express a …

Chimeric antigen receptors T cells (CAR T) had been used for treating various tumor
patients in clinic, and owned an incredible efficacy in part of malignancies. However, CAR T …

Recent reports on the impressive efficacy of chimeric antigen receptor (CAR)-modified T
cells against hematologic malignancies have inspired oncologists to extend these efforts for …

Chimeric antigen receptor (CAR) T-cells (CAR T-cells) are a promising therapeutic approach
in treating hematological malignancies. CAR T-cells represent engineered autologous T …